Intraventricular dyssynchrony among patients with left bundle branch block

Objective: To determine the frequency of intraventricular dyssynchrony among patients with left bundle branch block

Methods: The study was conducted at Hayatabad Medical Complex, Peshawar, from January, 2017 to July, 2017. All patients aged 18 years and above with Left Bundle Branch Block [LBBB] on ECG with or without heart failure were included in the study. Patients with valvular heart disease, predominant diastolic heart failure, acute coronary syndromes or coronary revascularization in last three months and atrial fibrillation were excluded. Tissue Doppler Imaging [TDI] parameters were measured from 2-D images in apical 4-chamber and 2chamber views. Consecutive non-probability sampling technique was used for sample collection

Results: Our study included 159 patients. Mean age was 52 years with SD +/- 2.74. Ninety-nine [62%] patients were male and 60 [38%] patients were female. One hundred and three [65%] patients had heart failure while 56 [35%] patients didn't have heart failure. More over in our study 124 [78%] patients had Intraventricular dyssynchrony while 35[22%] patients didn't have Intraventricular dyssynchrony

Conclusion: The incidence of Intraventricular dyssynchrony is high among patients with heart failure and left bundle branch block

Subclinical Hypothyroidism among local adult obese population

Objective: To determine the frequency of subclinical hypothyroidism in local adult obese population

Methods: The study was conducted at Hayatabad Medical Complex, Peshawar, from March, 2017 to August, 2017. All patients aged between 18 and 60 years with BMI of more than 29kg/m[2] were included in the study. Patients on lipid lowering drugs, with renal failure, hepatic failure and already diagnosed cases of thyroid dysfunction were excluded from the study. Thyroid functions were measured for all patients

Results: A total of 127 adults were included in the study in a consecutive manner. Mean age was 34.5 + 7.9 years of which 46.5% were male and 53.5% were female. Mean BMI was 32.05 +/- 2.06 kg/m[2]. The mean serum TSH was 3.13 +/- 1.10 mIU/L and mean serum thyroxine level was 1.08 +/- 0.25 ng/dl. Subclinical hypothyroidism was recorded in 15% of the study population

Conclusion: Subclinical hypothyroidism is highly prevalent in our population with BMI of more than 29kg/m[2]. Further studies are recommended on relationship between thyroid functions and BMI and its effect on cardiovascular functions