Central giant cell granuloma with aneurysmal bone cyst in a 28-year male patient: a rare concurrence

Central Giant Cell Granuloma [CGCG] is a benign tumor of jaw. As compared to males, females are more commonly affected. Mandible is the common site of occurrence. Aneurysmal bone cysts [ABCs] are cystic lesions which are expansile osteolytic blood-filled lesions. These are commonly seen in the mandible, and they also show gender-predilection towards females. Concurrence of both the lesions is rarely reported. The treatment of both CGCG and ABC depends upon the extent of the lesions as well as on their nature. Due to aggressive nature of the lesions, these usually cause disfigurement of the patients' face. Wide excision is the treatment modality for aggressive lesions to avoid recurrence. We present a case of 28-year male who showed CGCG along with ABC in the same lesion, a rare concurrence

Immunohistochemical expression of CD-117 [c-KIT], P-53 and Ki-67 in adenoid cystic carcinoma of palate

Adenoid cystic carcinoma [ACC] is a malignant tumor of salivary glands characterized histopathologically by biphasic epithelial tumor comprised of myoepithelial and ductal cells. There is a paucity of the literature regarding the immunohistochemical labelling of ACC arising in minor salivary glands. This paper reports an additional case of palatal ACC with an emphasis on its immunohistochemical staining using three different markers. Immunohistochemistry allows a better differentiation of ACC with its closest imitators, like polymorphous low grade adenocarcinoma [PLGA], considering that the latter is lesser aggressive and demands a lesser aggressive treatment approach

Angiomyxolipoma of tongue

Angiomyxolipoma is a rare histological variant of lipoma, characterized by proliferation of adipose tissue associated with a variable amount of myxoid stroma with numerous thick- and thin-walled blood vessels. An exhaustive literature review could reveal only 12 cases of angiomyxolipoma affecting subcutaneous tissue, subungual area and spermatic cord. In oral cavity, only 2 cases of angiomyxolipoma have been reported to date, one case in the buccal mucosa and one case in the floor of the mouth. Hence, this is only the third case of angiomyxolipoma affecting oral cavity and the first case of angiomyxolipoma of the tongue. We report a case of a 51-year male presenting with a swelling on the right lateral border of the tongue. The lesion was excised and microscopical examination confirmed the diagnosis of angiomyxolipoma