RESUMEN
OBJECTIVE@#To explore the feasible monitoring techniques for the buried free flap.@*METHOD@#Buried free flaps in reconstruction were monitored using combined monitoring techniques in five cases of advanced hypopharyngeal cancer The monitoring effects were analyzed retrospectively.@*RESULT@#The operations were carried out successfully and all the five patients got primary healing of incision without vascular crisis. Four patients need combined monitoring techniques to confirm the microcirculatory results of the buried free flap.@*CONCLUSION@#Application of Doppler combined with flap island was feasible on monitoring the blood supply of post-operative buried free flap, it is a good monitoring technique.
Asunto(s)
Anciano , Humanos , Masculino , Persona de Mediana Edad , Carcinoma de Células Escamosas , Diagnóstico por Imagen , Patología , Cirugía General , Colgajos Tisulares Libres , Neoplasias de Cabeza y Cuello , Diagnóstico por Imagen , Patología , Cirugía General , Neoplasias Hipofaríngeas , Diagnóstico por Imagen , Patología , Cirugía General , Hipofaringe , Periodo Posoperatorio , Estudios Retrospectivos , Carcinoma de Células Escamosas de Cabeza y Cuello , Colgajos Quirúrgicos , Ultrasonografía DopplerRESUMEN
<p><b>OBJECTIVE</b>To investigate the role of nasal mucosa fibrosis on radiation induced nasal mucosa injury.</p><p><b>METHODS</b>Seventy two male rats were randomly divided into two groups, control group and irradiation injured group (radiation dose were 40 Gy); the rats were killed 1 week, 2 weeks, 4 weeks, 8 weeks, 3 months and 6 months after the finish of radiation. The middle turbinates of the animals were removed. The pathological change of the nasal mucosa were observed with scanning electron microscope, transmission electron microscope, hematoxylin and eosin (HE), alcian blue-periodic acid-Schif (AB-PAS), and Masson Trichrome (MT). The Hyp content in nasal mucosa was measured with chemo-chromatometry.</p><p><b>RESULTS</b>After radiation, the pathological characteristics in early stage (within 4 weeks) was acute inflammatory reaction. The repair of nasal mucosa started 4 weeks after radiation, lasted to 6 months. The deposition of collagen in nasal mucosa could be found 1 week after irradiation and increased gradually.</p><p><b>CONCLUSION</b>Irradiation could induce a serials of pathological changes on nasal mucosa. The nasal mucosa fibrosis may be one of the reasons of persistent irradiation induced nasal mucosa injury.</p>