RESUMEN
Chondroid lipoma is a rare fatty tumor of soft tissues, especially in limbs and limb girdles. Though it is clinically benign, the main importance lies in its histological similarity with myxoid liposarcoma and chondrosarcoma, which have poorer prognosis. In our study, classical histological pattern of chondroid lipoma was confirmed on H&E and PAS stains with low mitotic count.
Asunto(s)
Adulto , Condrosarcoma/patología , Diagnóstico Diferencial , Humanos , Lipoma/patología , Masculino , Neoplasias de los Músculos/patología , Músculo Esquelético/patología , MusloRESUMEN
Prostatic lesions on routine H&E stain sometimes cause diagnostic dilemma specially in premalignant lesions like A.A.H. and P.I.N. Proliferative markers (AgNOR, P.C.N.A) are of great help in this grey zone. Total 50 cases studied and provisional diagnosis after HIE stain revealed that 37 cases were B.H.P., 5 cases were A.A.H., 1 case was P.I.N and 7 cases were adenocarcinoma. Proliferative marker study revealed AgNOR count of B.H.P as (0.4 -2.5)/cell, of A.A.H as (1.5-3.2)/cell, of P.I.N as 4.8/cell and adenocarcinoma as (4.3-5.4)/cell. P.C.N.A index of B.H.P was (2-8)%, of A.A.H (17-35)%, of P.I.N 40% and of carcinoma (54-82)%. Proliferative marker study was of great help in distinguishing between benign and malignant and specially premalignant lesions like A.A.H and P.I.N, where routine histopathology diagnosis was confusing. In the study, P.C.N.A was found to be superior to AgNOR since the values for interpretation was wider.