RESUMEN
To test the hypothesis that an increased plasma concentration of sialic acid, a marker of the acute-phase response, is related to the presence of diabetic retinopathy in type 1 diabetes mellitus or Insulin Dependent Diabetes Mellitus [IDDM].We investigated the relationship between plasma sialic acid concentration and diabetic retinopathy in a cross-sectional survey of 1,369 people with type 1 diabetes. Subjects were participants in the IDDM Complications Study, which involved diabetic centers of four different hospitals in Lahore. There was a significantly increasing trend of plasma sialic acid with severity of retinopathy [PAsunto(s)
Humanos
, Masculino
, Femenino
, Retinopatía Diabética/diagnóstico
, Ácido N-Acetilneuramínico/efectos adversos
, Estudios Transversales
, Albúmina Sérica
, Factores de Riesgo
, Triglicéridos
, Colesterol
, Hemoglobina Glucada
, Hipertensión
, Fumar
, Angiopatías Diabéticas
, Nefropatías Diabéticas
, Ácido N-Acetilneuramínico/sangre