RESUMEN
Anti-cyclic citrullinated peptide [anti-CCP] antibodies are highly specific markers for rheumatoid arthritis [RA] and useful for predicting rheumatoid arthritis [RA] development and progression. We assessed the diagnostic value of anti-CCP antibodies in our patients with RA. Anti-CCP antibodies and rheumatoid factor [RF] titers were determined in 247 serum samples: 128 from RA patients, 119 from control group p48 from healthy controls, 71 from patients with rheumatic disease other than RA or hematologic malignancies. There were 128 [93 females, 35 males] patients with rheumatoid arthritis and 119 [78 females, 41 males ] controls. The sensitivity of Anti-CCP was 66.40% for diagnosis of RA with a specificity of 94.11%. The sensitivity of RF was 69.53% and its specificity was 81.51% In our patients Anti-CCP has a moderate sensitivity but high specificity for diagnosis of RA