How to prepare a systematic review and meta-analysis: the methodological approach

Abstract Aim: This article aimed to provide to the authors a summary of the methodological approach to prepare a systematic review and meta-analysis. Methods: The instructions were established to support authors in preparing systematic reviews and meta-analyses, according to the required recommendations. Conclusion: The researchers should keep in mind that conduct a systematic review involves rigorous methodological criteria to identify and synthesize all relevant studies on a given topic defined a priori.