RESUMEN
To determine relationship between central corneal thickness [CCT] and intra ocular pressure [IOP]. The study subject were recruited from Ophthalmology Outpatient Department, Dow University of Health Sciences and Civil Hospital Karachi, from January to July 2006 Patients above 40 years of age of either gender having no history of ocular trauma, disease or surgery, neither suffering from systemic disorder nor taking medicine for any disease were studied for CCT and lOP. Goldman applanation tonometry and pachymetry were performed in a single session, IOP was measured by Goldman Applanation Tonometer [GAT]. Pachymetry was performed with ultrasonic pachymeter. Regression analysis was conducted to determine relationship. Six hundred eyes of 300 patients [male 53%, female 47%], were analyzed. Average IOP was 14.83 mmHg. Average CCT was 54K microns. A significant association was found between CCT and IOP [r=0.63, p<0.001]. CCT was found to be correlated linearly with increased IOP values [p<0.000]. A positive relationship exists between CCT and IOP