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Introduction: The SARS-CoV-2 virus is the infectious disease known as coronavirus disease (COVID-19). A lockdown was implemented across the nation in response to escalating infections and community transmission. Patients Living with Human Immunodeficiency Virus (PLHIV) must get therapy for the rest of their lives. Anti-Retroviral Therapy (ART) must be available and strictly adhered to in order to lower HIV-related morbidity and mortality and stop HIV transmission. ART continuity in PLHIV has been compromised globally by the COVID-19 epidemic. This research was done to find out how the pandemic affected PLHIV patient’s adherence to their ART regimens. Methods: For nine months, PLHIV visiting the ART centre in a tertiary care hospital in Bengaluru urban participated in this a prospective comparative study. Through systematic random sampling, 470 patients were chosen for the study. Data were gathered by one-on-one interviews using a standardised semi-structured questionnaire. The statistics used were mean, median, and z test for proportion. Results: The bulk of the study participants were male and between the ages of 41 and 50. The most frequent means of HIV transmission risk was heterosexual interaction. Before and during the COVID-19 pandemic, there was a large difference in the number of PLHIV/day visits. Opportunistic infections and first-line failures were more common and statistically significant during the COVID-19 pandemic. Prior to the pandemic, there was an average 94.84% adherence to ART, which dropped to 80.55% during the pandemic. The variation was substantial. Conclusion: The COVID-19 pandemic has impacted PLHIV medication adherence, and opportunistic infections have increased during this time.
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Background: COVID-19 vaccination in India was started from 16 January 2021. The vaccination for adolescents was started one year later. The only source of COVID-19 vaccination coverage is government data. There is a lack of external studies on COVID-19 vaccine coverage in this age group. In this regard, the present study was taken up with the objectives to assess the vaccination coverage of COVID-19 among adolescents aged 12-17 years and the factors associated with COVID-19 vaccine hesitancy. Methods: A coverage evaluation survey was done for assessing COVID-19 vaccination coverage among adolescents aged 12 to 17 years from September to December 2022 in the rural field practice area of a medical college near Bangalore. Results: Out of the 420 study subjects, 294 (70%) were fully vaccinated, 70 (16.6%) were partially vaccinated and 56 (13.4%) were unvaccinated. It was observed that the coverage of COVID-19 vaccine in the age group of 15 to 17 years was higher compared to 12 to 14 years. Conclusions: The COVID 19 vaccine coverage with two doses among adolescents aged 12-14 was 61.9% and 78.1% among 210 adolescents aged 15 to 17 years in the rural locality. The most common reason for partial vaccination was that the school did not provide the second dose and the most common reason for not being vaccinated is that the subject was not eligible for vaccination during the school vaccination campaign.
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A total of 88 Tuberculosis patients who registered for treatment were followed up until their completion. These patients were given treatment under the Government of India implemented RNTCP in the year 1999-2000 in a Tuberculosis unit in Bangalore Mahanagara Palike. Majority of the patients were male and from lower middle class In the present study the cure rate was 72.00 %, treatment completion was 80.55%, default patients were 22.72% and chronic cases were 6.25%.