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1.
Mem. Inst. Oswaldo Cruz ; 86(supl.2): 13-16, 1991.
Artículo en Inglés | LILACS | ID: lil-623932

RESUMEN

Eventhough the rationale behind the use of medicinal plantes in Brazil and Chine is different, twenty four species are used in both countries. Scientific name, vulgar name and uses in both countries along with their chemical constituents are listed.


Asunto(s)
Medicamentos Herbarios Chinos/uso terapéutico , Medicina Tradicional China/métodos , Plantas/química , Brasil , China
2.
Braz. j. med. biol. res ; 22(11): 1397-9, 1989. ilus, tab
Artículo en Inglés | LILACS | ID: lil-83145

RESUMEN

The anti-inflammatory activity of a purified fraction of the rhizome of Wilbrandia (cf) verticillata, which contains two novel norcucurbitacin glucosides, is reported. The increase of vascular permeability induced by acetic acid in mice (N = 5) was inhibited 69% and 90% by 50 and 100 mg/kg of the purified fraction, po (P<0.01). Acetylsalicylic acid (200 mg/kg), po, inhibited the response by 62% under the same conditions (P<0.05). The purified fraction (100 mg/kg, po) also significantly inhibited paw swelling in the rat formaldehyde-induced arthritis model on 8 of 10 days and reduced the swelling by 63% on day 10. Dexamethasone (1 mg/kg, ip) was more effective than the extract under the same conditions. These data partially characterize the anti-inflammatory activity of the purified fraction from this plant which is used in Brazilian folk medicine for the treatment of arthritis and related disorders


Asunto(s)
Ratas , Animales , Femenino , Acetatos/antagonistas & inhibidores , Artritis Experimental/etiología , Permeabilidad Capilar/efectos de los fármacos , Formaldehído/antagonistas & inhibidores , Extractos Vegetales/farmacología , Ratas Endogámicas , Triterpenos/análisis , Triterpenos/farmacología
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