Hormone levels in Russell's viper bite follow-up patients

Studies of cliniccal features of hypopituitarism and/or any endocrine daficiency and hormone levels were carried out in systemic envenomed Russell's viper bite victims of more than one year duration. Eighteen follow-up patients with history of post viper bite ranging from one to seven years were studied. Serum cortisol were assayed in all but serum ACTH, HGH and urinary cortisol and HGH were made in four patients. Eight were found to have clinical evidence of endocrine deficiency and their hormone levels were on the low side, although statistically not significant. Symptomless patients also have abnormal pituitary function. Chronic ill-health with vague clinical presentation in post viper bite cases should always raise the possibility of chronic pituitary dysfunction.

Circulating and urinary cortisol, ACTH & HGH levels of normal Myanmar subjects

Cortisol, adrenocorticotropic hormone (ACTH), human growth hormone (HGH), overnight urinary cortisol and HGH levels were measured in 31 apparently normal healthy volunteers (21 males and 10 females) at the Thayawady Township Hospital. Measurement of circulating hormonal levels was performed by using commercial radioimmunoassay kits. All volunteers were admitted to the hospital for a period of 48 hours and cortisol, ACTH, HGH were measured four times in 24 hours (9:00 hr, 12 noon, 18 hr and 24 hr) consecutively for 48 hours. Overnight urinary cortisol and HGH levels were also measured after a protein load was given on the second night. Serum ACTH level was 15.82 uU/L (range 0.02 to 150.0 uU/L) and the average 24 hour serum HGH level was 7.55 mU/L (range 0.01 to 37.0 mU/L). Serum cortisol was found to be in the range of 21.0 nmol/L to 700.0 nmol/L with a 24 hr average of 227.95 nmol/L. Overnight urinary cortisol and HGH ranged from 0.089 to 27.7 ug and 4.0 to 230 uU respectively.

Normal levels of SGO-T and SGP-T in healty Burmese adults

A variable range of normal SGO-T and SGP-T and activities have beenreported by various authors. With the colorimetric method of Reitman and Frankelthe normal levels of SGO-T and SGP-T in 120 Burmese adults were studied. Specimens for analysis were obtained from healthy active blood donors and factory workers. The results were analysed statistically. The mean SGO-T was 23.6+-4.6R-F units, with a normal range of 14.4 to 32.8 R-F units, while that of the SGP-T was 18.6+-1.4 R-F units, with a normal range of 9.8 to 27.4 R-F units. Although the sex difference in SGO-T shows statistical significance,no significant difference was found between the two sexes in SGP-T. The correlation coefficients show thatthere is no relation of age either to SGO-T activity or SGP-T activity. Both distributions of SGO-T and SGP-T follow a normal distribution.