A Case of Papillophlebitis in 21-year-old Healthy Male Adult

Papillophlebitis is a central retinal vein occlusion with papillitis and usually occurs in a young healthy adult. It is usually unilateral and symptoms include mild visual impairment, floaters of metamorphopsia. In contrast to central retinal vein occlusion in old age, there is usually no association with diabetes, hyopertension and cardiovascular disorder. Usually the retinal hemorrhage resolves spontaneousaly after several months and the papillitis decreases with good visual outcome. The authors experienced a papillophlebitis in 21-year-old male with sudden visual decrease of left eye. He had no systemic diseases. The patient recovered good vision with systemic steroid treatment. We report this case with review of previous reports.

Comparison of the Retinal Microvasculature between Normal and Diabetic Rats Using Trypsin & DNase Digestion Technique

Trypsin and DNase digestion technique has become a retinal digestion technique for studying diabetic retinopathy. We tried osmotic digestion method with DNase and compared the quality of preparation of retina and microvascular change with trypsin digestion in normal and diabetic rats. Streptozotocin-induced diabetic rats were sacrificed at 9, 18, 27weeks in 6 rats. Right retinas were digested with 3% trypsin while left wer digested with 0.1% DNase. For control, 18 normal rats were sacrificed at the same time. DNase was superior to trypsin for retinal preparation on the stainability, the degree of separating nonvascular fissue from vascular net, the degree of preservation of vascular net in normal & diabetic rats. In diabetic rats, the number of pericyte decreased significantly with age, which not in normal rats(p=0.0023) We suggest DNase digestion technique as an new alternative for trypsin digestion technique in the study of microvascular change of diabetic retinopathy.

Pupil Size in the Dark in Normal Adults

Recently refractive corneal surgery has been increasing and intraocular lens implantation is a routine procedure during cataract surgery. Many people have various activities in the evening such as night driving, thus it may be very important measuring the pupil size in the dark in determining the size of the optical zone. We measured pupil size of sixty normal adult candidates in darkness of 0, 20, 60, 100 lux and also in the bright illumination of 200 lux for comparison using near lens camera and slide film. The pupils became larger with younger age and increased darkness. Pupil Size(log mm) = 4.57 - 0.0388 X Age(year) - 0.005 X Luminance(lux). The average pupil size of all age groups were 7.0mm, 6.56mm, 5.97mm, 5.4mm sequencially in darkness and 4.77mm in brightness(200 lux). The average pupil size of 20~30 year old group who are socially active even at night was 7.18mm and 8.4mm in maximum. This has significant meaning clinically. Additionally the size of pupil became larger with increased corneal diameter and the amount of anisocoria tended to be greater with the increase of the darkness.

Effect of Induced Anisometropia on Stereoacuity by Far and Near Distance Random Dot Stereo Test

Induced refractive errors or anisometropia are known to cause reduction in stereoacuity. We compared the reduction of stereoacuities in anisometropia between far and near stereotests to determine the value of these tests as a screening tool of anisometropia. The far stereoacuity of 3m distance was tested with a red-green RDS developed with a color computer, and the near stereoacuity with TNO test in 10 normal adult volunteers. The effect of anisometropia. on the stereoacuity was tested by placing spherical lenses in 0.5 D steps bfore one eye(-2.0 D ~ +2.0 D). Stereoacuities tested at far showed a more rapid decrease than those at near as the power of the lenses was increased. The plus lenses showed more deteriorating effect on the stereoacuity than the minus lenses. And all subjects showed more than 620 arc seconds of stereoacuities with more diopter than +1.5D spherical lens. The far stereotest seems to be a more sensitive screening tool of anisometropia than the near stereotest especially in the mild degree(less than 2.0 D) of anisometropia.