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Journal of Zhejiang University. Medical sciences ; (6): 307-312, 2007.
Artículo en Chino | WPRIM | ID: wpr-271530

RESUMEN

Parthenogenetic activation is a procedure that an oocyte at meiosis II stage is activated into mitosis by some chemical or physical stimulation other than a sperm and the embryo is formed in the absence of any contribution from a male gamete. The activation of oocyte is the result of calcium ion oscillations and deactivation of some cytokines such as maturation promoting factor, mitogen-activated protein kinase and cytostatic factor. Parthenogenetic activation is artificially induced by various kinds of physical and/or chemical methods. The main activation method of human oocyte is chemical methods. The rates of activation and cleavage depend on the age, origin,and culture conditions of the oocyte.


Asunto(s)
Animales , Femenino , Humanos , Adenina , Farmacología , Calcio , Metabolismo , Cicloheximida , Farmacología , Citocinas , Metabolismo , Oocitos , Metabolismo , Partenogénesis
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