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Rev. Inst. Med. Trop. Säo Paulo ; 34(6): 601-8, nov.-dez. 1992. tab, graf
Artículo en Inglés | LILACS | ID: lil-134566

RESUMEN

From each of a group of 217 adult males selected through enzyme-immunoassay or skin-test (Group A), six stool samples were examined by both the Lutz/Hoffman, Pons & Janer (Lutz/HPJ) and Kato/Katz methods. In addition, one oogram of the rectal mucosa was performed. By these methods, schistosomiasis was detected in 44.7%, 47.5% and 40.1% of the individuals respectively. To evaluate the methods in the assessment of cure, the last 40 patients from group A, treated with a single oral dose of oxamniquine at 15 mg/kg were followed up for six months (Group B). The criteria for parasitological cure included three stool examinations by Kato/Katz and Lutz/HPJ methods, one, three and six months post-treatment and a rectal biopsy between the fourth and sixth months post-treatment. The examinations were negative in 87.5%, 90% and 95% of the patients, respectively. The efficacy of oxamniquine was 82.5% when the three methods were considered together and there was no statistically significant difference between the sensitivity of the individual methods


Asunto(s)
Animales , Humanos , Masculino , Heces/parasitología , Recto/patología , Schistosoma mansoni/aislamiento & purificación , Esquistosomiasis mansoni/diagnóstico , Adolescente , Adulto , Biopsia , Brasil , Estudio de Evaluación , Métodos , Personal Militar , Oxamniquina/administración & dosificación , Recto/parasitología , Esquistosomiasis mansoni/tratamiento farmacológico , Esquistosomiasis mansoni/parasitología , Esquistosomiasis mansoni/patología , Factores de Tiempo
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