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Acta Pharmaceutica Sinica B ; (6): 1274-1285, 2021.
Artículo en Inglés | WPRIM | ID: wpr-881198

RESUMEN

Liver is the most common metastatic site for colorectal cancer (CRC), there is no satisfied approach to treat CRC liver metastasis (CRCLM). Here, we investigated the role of a polycomb protein BMI-1 in CRCLM. Immunohistochemical analysis showed that BMI-1 expression in liver metastases was upregulated and associated with T4 stage, invasion depth and right-sided primary tumor. Knockdown

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