Advances in study on regulation of hair pigment expression by natural products / 中草药

Hair color is affected not only by genetic, age, and environmental factors, but also by the regulation of many cytokines and proteins. The generation of melanin is mainly regulated by POMC, α-MSH, MC1R, MITF, tyrosinase, TRP-1, TRP-2, ASIP, etc. Hair color anomaly is often considered to be a feature of aging which brings great psychological pressure to the people, but the treartment by relevant drugs is still blank. This article summarizes the effect target and the function ways of those natural medicines with great efficacy on the treatment of hair graying. This review may provide some theoretical basis for the application of natural medicines in the treatment of hair graying.