RESUMEN
Objective To assess the value of small bowel computed tomography ( CT ) scan combined with single balloon enteroscopy ( SBE) for the diagnosis and treatment of Peutz-Jeghers syndrome ( PJS) . Methods CT scan was performed in cases that were clinically suspected or proved PJS for the number, size, location and relative acute complications of polyps in the small intestine. Single balloon enteroscopy was used to resect small intestinal polyps according to CT findings. The number of observed polyps in diagnosis, numbers of resected polyps, procedure duration and complications in endoscopic therapy were analysed. Results Polyps were found in the small intestine in all patients. There were 68 polyps whose diameter was 1-4 cm. Nine SBE procedures were completed in these patients. The mean procedure time was 120 min. A total of 65 polyps were detected by SBE with 95. 59％ concordance to CT results. A total of 52 polyps were resected under endoscopy, the largest diameter of which was 4 cm. No complications were observed after SBE. Conclusion Combination of small bowel CT scan and SBE is safe and effective for diagnosis and treatment of PJS patients, which is worth recommendation.
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Objective To explore the characteristics of cognitive function in patients with the first-episode and chronic schizophrenia. Methods 83 cases of first-episode schizophrenia patients, 77 cases of chronic schizophrenia patients and 75 healthy volunteers from January 2013 to June 2014 were selected. MATRICS consensus cognitive battery (MCCB) test was conducted on them and their cognitive profile patterns and characteristics of cognitive function impairment were analyzed. Results Compared with the healthy control group, the first-episode schizophrenia patients and chronic schizophrenia patients got hurt in psychomotor speed, attention, working memory, verbal learning and memory, visual learning and memory, reasoning and problem solving ability, social cognition and other areas in the MCCB (P<0.05). There were differences in comparing working memory and social cognition of the first-episode schizophrenia patients and chronic schizophrenia patients (P<0.05). Conclusion The first-episode schizophrenia patients get less injury than chronic schizophrenia patients in the working memory and social cognition. Whether first-episode schizophrenia pa-tients or chronic schizophrenia patients, they are impaired compared with the normal population in cognitive function.