RESUMEN
To document the common microorganisms causing UTI in human and their resistance to currently used antibiotics. PMRC, Research Center Khyber Medical College Peshawar. Retrospective analytical study. Jan 2000 to June 2003. Evaluation results of 597 urine cultures performed during the period, on clinically suspected referred subjects. Bacterial growth was obtained in 35% samples. Common micro organisms in decreasing order of yield are E. CoIi, Klebsiella, Staph aureus, Proteus species and pseudomonas isolated from 80, 7.1, 5. and 1.5% samples respectively. 100% sensitivity is observed for imipenum. Efficacy next in decreasing order was for Amikacin, Tarivid, Ciproxin and Rocephin. Esch. Coli is the predominant etiological organism of UTI and imipenum is the drug of choice to which over 80% of all the different organisms are sensitive. Constantly changing sensitivity pattern of the organisms responsible for UTI demands a periodic check for better selection of drug and reduction of consequences of the disease