Measurement properties of the Brazilian version of the Kidney Symptom Questionnaire

SUMMARY OBJECTIVE: The aim of this study was to measure the reliability, internal consistency, and construct validity of the Kidney Symptom Questionnaire for the Brazilian population. METHODS: This is a cross-cultural adaptation and questionnaire validation study. We included native Brazilians of both sex aged>18 years, as well as hypertensive and/or diabetic patients. All participants were assessed using Screening for Occult Renal Disease, EuroQol 5 Dimensions, 36-Item Short Form Survey, and the Kidney Symptom Questionnaire. We used Spearman's coefficient (rho) to measure the correlations between the Kidney Symptom Questionnaire and other instruments; Cronbach's alpha to measure internal consistency; and intraclass correlation coefficient, standard error of measurement, and minimum detectable change to measure test-retest reliability. RESULTS: The sample was formed by 121 adult participants, mostly female, with systemic arterial hypertension and/or diabetes mellitus. We found excellent reliability (intraclass correlation coefficient≥0.978), adequate internal consistency (Cronbach's alpha≥0.860), and adequate construct validity on the Kidney Symptom Questionnaire domains; besides, we observed significant correlations between the Kidney Symptom Questionnaire and other instruments. CONCLUSION: The Brazilian version of the Kidney Symptom Questionnaire has adequate measurement properties to assess chronic/occult kidney disease in patients who do not require renal replacement therapy.

Una aplicación digital aumenta la adherencia al tratamiento farmacológico en síndromes coronarios / Use of a smartphone application to increase adherence to medical treatment

Resumen La adherencia al tratamiento médico farmacológico en pacientes que cursaron una hospitalización por un síndrome coronario agudo (SCA) es deficiente. El objetivo primario fue demostrar que, mediante la utilización de una aplicación digital para smartphones, se incrementa por lo menos un 30% la adherencia al tratamiento, en relación al grupo control, en pacientes con SCA. Se realizó un estudio unicéntrico aleatorizado, controlado, con distribución 1:1, simple ciego, que comparó la utilización de una aplicación para smartphones (grupo intervención), frente a la indicación de tratamiento farmacológico por escrito (grupo control), en términos de adherencia médica farmacológica total, en 90 pacientes que cursaron internación por un SCA. La adherencia fue determinada mediante el Cuestionario de Adherencia a la Medicación de Morisky. El paciente se consideró como "totalmente adherente" de obtener un puntaje perfecto (8/8 puntos). El período de seguimiento fue de 90 días posterior al egreso hospitalario. La edad promedio fue 63 ± 9 años, con el 76% de sexo masculino. El objetivo primario ocurrió en 67.4% (31/46) del grupo intervención vs. 20.5% (9/44) del grupo control (p < 0.001). En pacientes que cursaron una hospitalización por SCA, la utilización de una aplicación digital para smartphones incrementó la adherencia al tratamiento médico farmacológico.

Abstract Adherence to cardiovascular medications following acute coronary syndrome hospitalization is generally poor. The primary outcome was to demonstrate that the use of a digital application for smartphones increases the adherence to pharmacological treatment by 30 % in relation to the group without intervention, in patients with an acute coronary syndrome with or without ST segment elevation. In this unicentric, single blinded, randomized controlled trial with 1:1 allocation we compared the use of a digital application for smartphones and written information as standard of care, for the adherence to pharmacological treatment in 90 patients admitted to the hospital with an acute coronary syndrome. Adherence to medical treatment was measured by Morisky Medication Adherence Scale. A patient is considered to have good adherence when score is perfect (8 points). The follow up period was 90 days after hospital discharge. The mean age of the population was 63 ± 9 and 76% were male. At 90 days, 67.4% (31/46) of patients using the smartphone application were adherent compared with 20.5% (9/44) of patients in the control group (p < 0.001). In patients with acute coronary syndrome, the use of a smartphone application increased the medication adherence compared with the standard of care.

Antimicrobial activity in cultures of endophytic fungi isolated from Talinum triangulare

Endophytic fungi colonize the interior of plants without causing damage and act in symbiosis with their host. They are also potential sources of compounds with potential applications in industry, agriculture, and medicine, Thus, this study aimed to isolate and identify the endophytic fungi medicinal plant Talinum triangulare and evaluate its potential for the production of antimicrobial substances using the disk diffusion technique and testing in liquid medium front of Staphylococcus aureus ATCC SA 6538, Pseudomonas aeruginosa ATCC PA 0030, and Corynebacterium diphtheria ATCC 27012. Corynebacterium diphtheria was isolated from 3 fungi of the genus Trichoderma and Penicillium, with only the genus Trichoderma fungi showing antimicrobial activity.

O circo na formação inicial em educação física: um relato autoetnográfico / The circus in initial training in physical education: an autoethnography report / El circo en la formación inicial en educación física: un informe autoetnográfico

Resumo O estudo apresenta, a partir da perspectiva autoetnográfica, uma possibilidade de sistematização dos saberes circenses na formação inicial em educação física. Para tal, recorremos à observação participante durante um semestre letivo (40 horas) numa instituição de ensino superior pública do Estado de São Paulo. O diário de campo, os registros fotográficos das aulas e as conversas informais dos discentes constituíram-se os instrumentos de pesquisa. Os resultados demonstraram a excelente receptividade dos alunos, com experiências que favoreceram a autonomia e a tomada de decisão. Identificamos que a existência pregressa da disciplina no currículo foi um agente facilitador. Outros fatores dificultadores foram o elevado número de alunos por turma e a reduzida carga horária da disciplina.

Abstract The study presents on autoethnography as a research method, a possibility of systematisation circus knowledge in initial training in physical education. To this end, participant observation was used during an academic semester (40 hours) in a public institution of higher education in the State of São Paulo in Brazil. Field journal, photographic records of classes in addition to the informal conversations students were research instruments. Results demonstrated excellent receptiveness on the part of the students, with experiences that favored the autonomy and decision making. Early existence of the discipline in the curriculum was an agent facilitator. Other factors the process were the large number of students per class and the reduced workload of the discipline.

Resumen El estudio presenta, desde la perspectiva autoetnográfica, una posibilidad de sistematización del conocimiento circense en la formación inicial en educación física. Para ello, se ha recurrido a la observación participante durante un semestre lectivo (40 horas) en un centro público de enseñanza superior del estado de São Paulo. En la investigación se utilizaron un diario de campo, registros fotográficos de las clases, así como conversaciones informales con los alumnos. Los resultados demostraron la excelente receptividad por parte del alumnado, con experiencias que favorecieron la autonomía y la toma de decisiones. La temprana existencia de la disciplina en el plan de estudios fue un agente facilitador. Otros factores, como el elevado número de estudiantes por grupo y la reducida carga horaria, se identificaron como dificultades.

Quiste epitelial esplénico como causa infrecuente de dolor abdominal. reporte de caso / Splenic epithelial cyst as an unusual cause of abdominal pain. a case report

Se reporta el caso de una joven con esplenomegalia, que consulta por dolor abdominal crónico en hipocondrio izquierdo. Los estudios mostraron un quiste tabicado de gran tamaño, con desplazamiento de órganos. Se realizó una esplenectomía total, confirmándose al estudio histopatológico, un quiste epitelial esplénico

We report the case of a girl with splenomegaly, who consults for chronicabdominal pain in the left hypochondrium. The studies showed a largecyst with organ displacement. A total splenectomy was performed, confirmingto the histopathological study, a splenic epithelial cyst.

As práticas circenses no “tear” da formação inicial em educação física: novas tessituras para além da lona / Las prácticas circenses en el “telar” de la formación inicial en educación física: nuevas texturas más allá de la carpa / Circus practices in the “loom” of initial training in physical education: new textures in addition to the canvas

Este artigo analisa os processos de implementação das práticas circenses na formação inicial em Educação Física em duas Instituições de Ensino Superior do Estado de São Paulo. Para isso, entrelaçou-se a análise documental dos projetos político pedagógicos das instituições e dos programas das disciplinas relacionadas à temática circense às entrevistas narrativas com professores, gestores e alunos. Constatou-se que os processos investigados foram sedimentados no contexto de intensas histórias de mobilizações e embates, de trajetórias de pesquisa na busca pela construção de sólidos conhecimentos para além dos limites que os tempos e espaços institucionais impõem.

This paper analyzes the processes of implementation of circus practices in initial training in Physical Education at higher education institutions in the State of São Paulo, Brazil. The document analysis of the political-pedagogic projects of the institutions and programs of disciplines related to the subject of circus were interwoven to narrative interviews with teachers, managers and students. The processes investigated were found to be based on intense stories of mobilizations and clashes, on research trajectories seeking to build solid knowledge beyond the limits imposed by institutional times and spaces.

Este artículo analiza los procesos de implementación de las prácticas circenses en la formación inicial en Educación Física en dos instituciones de educación superior del Estado de São Paulo, en Brasil. Para ello, se entrelazaron el análisis documental del proyecto político pedagógico de las instituciones y los programas de las disciplinas relacionadas con la temática circense y las entrevistas narrativas con profesores, administradores y alumnos. Se constató que los procesos investigados resultan de intensas historias de movilizaciones y enfrentamientos, de trayectorias de investigación en buscando construir sólidos conocimientos más allá de los límites que imponen los tiempos y espacios institucionales.

Biodegradation of stored jet fuel by a Nocardia sp. isolated from contaminated soil

The aim of this study was to investigate the potential of degradation of an autochthonous bacterial strain, isolated from petroleum derivatives contaminated soil samples against jet fuel hydrocarbons. The autochthonous bacterial strain was characterized as Nocardia sp. Evaluation of their degrading abilities was carried out by presumptive assays as redox indicator test and by observations of surface tension decreases in aqueous medium. Degradation of jet fuel hydrocarbons was evaluated by chromatographic methods. Experiments were performed in flasks at two biostimulation rates. A bacterial strain of Pseudomonas aeruginosa UFPEDA 39 was utilized as a reference microorganism. The bacterial strain, identified as Nocardia sp, demonstrate high ability to degrade jet fuel compounds as well as to produce surface active compounds when compared to the reference microrganism.

O presente estudo objetivou a investigação da capacidade degradadora de uma linhagem bacteriana autóctone (isolada de amostras de solo contaminadas com derivados de petróleo) contra hidrocarbonetos de querosene de aviação. A linhagem foi caracterizada como Nocardia sp. A avaliação do seu potencial degradador deu-se realizada mediante testes com indicador redox e observações na redução da tensão superficial na fase aquosa. A degradação do querosene foi avaliada por métodos cromatográficos. Os experimentos foram realizados utilizando-se duas taxas de bioestímulo. Uma linhagem bacteriana Pseudomonas aeruginosa UFPEDA 39 foi utilizada como referência. A linhagem autóctone demonstrou alta eficiência na degradação de hidrocarbonetos do querosene bem como para produzir compostos ativos de superfície quando comparada com a linhagem de referência.

Biodegradation of diesel oil by yeasts isolated from the vicinity of suape port in the state of Pernambuco - Brazil

The aim of this work was to investigate the potential of the diesel oil degrading yeasts to use them in bioremediation of areas contaminated by this pollutant. The cultures, identified as Rhodotorula aurantiaca UFPEDA 845 and Candida ernobii UFPEDA 862, were selected at the initial stage. In the course of the biodegradation assays, C. ernobii degraded tetradecane, 5 methyl-octane and octadecane completely and decane (60.8 percent) and nonane (21.4 percent) partially whilst R. aurantiaca presented degradation percentages of 93 percent for decane, 38.4 percent for nonane and 22.9 percent for dodecane.

O objetivo deste trabalho foi investigar a potencialidade de leveduras que degradam óleo Diesel, visando aplicação em processo de biorremediação de áreas impactadas pelo referido poluente. As culturas, identificadas como Rhodotorula aurantiaca UFPEDA 845 e Candida ernobii UFPEDA 862, foram as selecionadas na etapa inicial. Quanto aos ensaios de biodegradabilidade, a levedura Candida ernobii UFPEDA 862 degradou totalmente: tetradecano, 5 metil-octano e octadecano, e parcialmente decano (60,8 por cento) e nonano (21,4 por cento), enquanto que a Rhodotorula aurantiaca UFPEDA 845 apresentou percentuais de degradação de 93,0 por cento para decano, 38,4 por cento para nonano e 22,9 por cento para dodecano.