RESUMEN
In Japan, few health care professionals have a basic understanding（core competency）of the design of clinical research and statistical analysis. We developed a blended distance–learning program comprising face–to–face lectures with e–learning for busy health care professionals who work in the clinical settings to achieve core competency in clinical research. The purpose of this study was to examine the educational effects of this program.<br>1）Four months after the end of the program, 64％ of the participants had started to conduct clinical research.<br>2）This program may increase the number of research colleagues that can discuss clinical research.<br>3）This program could enhance the confidence（self–efficacy）of health care professionals in clinical research.