RESUMEN
Background: Breast lump have varied pathology and different techniques are available to diagnose it. But fine needle aspiration cytology (FNAC) is highly accurate, rapid, and reliable tool for diagnosing breast lump. It helps the clinician to plan correct management. Aim: Aim of this study was to evaluate role of FNAC in diagnosis of palpable breast lesions in term of sensitivity, specificity, accuracy, positive predictive value, negative predictive value and to compare cytopathological findings of breast lesions with histopathology wherever possible. Materials and methods: This study was carried out on 234 patients, all presented with breast lump in pathology Department, GMERS medical college, Valsad over a period of January 2015 to May 2017. Out of 234 patients 2 were male. Cytological diagnoses were correlated with histopathological findings. Results: Cytopathologically lesions were categorized as non-neoplastic 16(6.83%), benign 122(52.13%), malignant 30(31.19%) suspicious 12(5.12%) and unsatisfactory aspirates 11(4.70%). Of these 234 cases 69(29.48%) cases were available for histopathological examination, of which 39 benign cases and 24 malignant cases were similarly diagnosed on histopathology. 5 suspicious cases and 1 unsatisfactory aspirate on FNAC were turned out to be malignant on histopathology. So sensitivity was 80%, specificity 100%, positive predictive value 100%, negative predictive value 86.6% and diagnostic accuracy 91.30%. Conclusion: FNAC is a simple and reliable method for diagnosis of breast lump with quite accuracy and avoiding unnecessary surgery. The results of FNAC show high degree of correlation with Sunita Mistry, Jignasha Patel, Kamlesh Shah, Ajit Patel. Cytological study of palpable breast lumps with their histological correlation in a tertiary care hospital. IAIM, 2018; 5(1): 11-16. Page 12 histopathology reports and that proves that the procedure has high sensitivity, specificity and diagnostic accuracy.
RESUMEN
Background: Carcinoma of the breast is the most common malignancy in adult women and the second leading cause of cancer death in women. There is an uncertainty over natural history and factors leading to emergence of cancer of breast in women as well as in men. Aims & Objective: To study the various morphological types of malignant lesions and their age distribution, from Mastectomy and Post lumpectomy Mastectomy received from in and around Ahmadabad district, at Department of Pathology, Smt NHL MMC and Sheth VS Hospital, Ahmedabad. Material and Methods: Out of the specimens of breast which presented as mastectomy and post lumpectomy mastectomy specimens of breast to the Department of Pathology, Smt NHL MMC and Sheth VS Hospital, Ahmedabad for histopathological examination, 100 cases were taken up for this study. Detailed clinical data were noted as per the proforma with emphasis on history, gross examination and microscopic examination. Results: Majority of cases were carcinoma (87%). Majority of women (63%) were of age 41-60. Painless lump (77%) was found as most common symptoms, while nipple retraction was found in 3% cases and Peaude orange skin was found in 1% cases. Majority of patients had lump in the left breast (53%) followed by right breast (47%). 40% of patients presented with lump in the upper outer quadrant and 11% in lower outer quadrant. Out of the total 88 carcinomas of breast encountered, 85.2%, were Infiltrating Duct Carcinoma [IDC (NOS)], 1.1% were Ductal Carcinoma in Situ (DCIS), 1.1% each of mucinous carcinoma, invasive papillary carcinoma and acinic cell carcinoma, 2.2% were metaplastic carcinoma and 6.8% were invasive lobular carcinoma. Most of tumour was T3 (53.48%) followed by T2 (29.06%). In the case of pathological staging The majority of patients were present in stage IIIA (25.58%), stage IIB (24.41%) and stage IIIC (22.09%), followed by Stage IIA (18.60%). Vascular invasion was 21.3% in the case of IDC, 66.6% in the case of ILC and 25% in the case of stromal carcinoma. Conclusion: This study highlights the importance of histopathological examination in breast lumps not only in establishing the final diagnosis, but also in predicting the prognosis by typing, staging and grading malignant neoplasm of breast.