case of severe and recurrent painless thyroiditis requiring thyroidectomy

To report a case of severe and recurrent painless thyroiditis requiring thyroidectomy. A 47-year-old man who presented with severe thyrotoxicosis was found to have extremely low radioactive iodine uptake, negative TSH receptor antibodies, and normal C-reactive protein; these findings suggested a diagnosis of painless thyroiditis. Due to the severity and recurrence of thyrotoxicosis, surgical resection of the thyroid gland was performed to prevent a thyrotoxic storm. Histological examination revealed typical lymphoid infiltration of the thyroid gland. This case illustrates that a patient with painless thyroiditis was successfully treated with surgery

Amiodarone-induced thyrotoxicosis with thyroid papillary Cancer in multinodular goiter: case report

To report a case of amiodarone-induced thyrotoxicosis [AIT] concomitant with thyroid cancer in multinodular goiter [MNG]. A 61-year-old man treated with amiodarone for 5 years presented with mild sweating. He was found to have AIT simultaneously with thyroid papillary cancer and MNG. Administration of amiodarone was stopped, and he was treated with methimazole for AIT. Five weeks after the initial treatment, thyroid function normalized. Total thyroidectomy was considered to enable use of amiodarone again. This case showed that thyrotoxicosis, MNG and amiodarone may contribute to thyroid carcinogenesis. Amiodarone should be carefully commenced in cases with MNG