RESUMEN
To evaluate the role of Doppler study done in the second trimester of pregnancy in the prediction of pre eclampsia. Prospective clinical trial. Department of Obstetrics and Gynecology, Kasr El-Aini Hospital. One hundred pregnant women with singleton gestation, in the second trimester, at risk of pre-eclampsia were subjected to Doppler ultrasound at 18-26 wks to measure S/D ratio, Resistance index RI, Pulsatility index of the uterine artery PI, in addition to the presence or absence of a diastolic notch. All women were followed up till delivery. There were significant differences between patients who developed PIH [eleven cases] and those who didn't develop as regards Doppler parameters at mid trimester including PI. RI, S/D ratio and the presence of diastolic notch. Doppler ultrasound at midtrimester identifies group of women at high risk for the subsequent development of pre-eclampsia for whom we can start preventive regimens