Immounopathology of primary pterygia

To evaluate the role of immunological mechanisms in the etiology off primary pterygia, 20 cases of surgically excised primary pterygium presenting at various clinical stages were examined with morphological and immunohistochemical methods, and compared with normal conjunctiva excised from the nasal part of the limubs. B5-fixed, paraffin-embedded tissue was stained with anti-bodies directed against T-cells, B-cells, macrophages, Langerhans cells, HLA-DR antigens and immunoglobulins. Increased numbers of dendritic cells variably expressing s-100 protein, HLA-DR antigens and/or the LN2-marker, were observed both in the epithelium and underlying stroma. In addition, the elastotically degenerated stroma contained variable numbers off KP1 + macrophages. T- and B- lymphocytes as well as immunoglobulin-containing plasma cells were generally inconspicuous

Diagnostic and therapeutic value of the replica technique in herpetic keratitis

The recommendation of corneal replicas in the management of superficial herpetic keratitis serves a dual purpose. The first purpose is diagnostic to facilitate histopathological examination of the intact corneal epithelium including the herpetic lesions. The second purpose is therapeutic to promote uneventful healing of the corneal ulcer without any complications and perhaps to reduce the recurrence rate. The causes of recurrences may be either due to stromal affections in which the epithelial lesion only was cured. In cases of simple epithelial herpetic keratitis, corneal replicas proved to be effective in healing the condition within 3-5 days without any complications. If the recurrence has occured and it is very low percentage, it may be attributed to insufficient amount of replica or missed diagnosis of significant stromal affection

modified trabeculectomy procedure trabeculocanalectomy

An easy and safe surgical technique ensuring the excision of a block of the canal of Schlemm and its adjacent trabeculum is described in detail. The operation has the advantage of precise localization and orientation of the block of tissue to be excised