Haematological side effect of Helicobacter pylori eradication

The effect of Helicobacter pylori infection on systemic disorders is not well understood. This study was to evaluate the effect of H. pylori eradication on blood count, differential leucocytic count and RBCs indices. In this study, atotal of 115 H. pylori positive patients underwent eradication triple therapy for one week, with cured 100 patients. Complete blood count, RBCs indices and differential leucocytic count were analyzed before 2 and 12 weeks after eradication for the cured patients. The results showed that two weeks after H. pylori eradication, platelets count significantly increased but total leucocytic counts and neutrophils were significantly reduced. After three months, RBCs count, Hb concentration, MCV and MCHC were significantly increased, but lymphocytic counts was significantly reduced

Portal vein parameters in Egyptian patients with spontaneous bacterial peritonitis

Spontaneous bacterial peritonitis [SBP] is a severe complication of cirrhosis and the role of portal hypertension in the development of SBP has been suggested. This study assessed the portal vein [PV] haemodynamic changes in patients with SBP. The study was conducted on 20 ascitic patients with SBP [GI], 20 ascitic patients without SBP [GII], 20 cirrhotic patients without ascites [GIII] and 20 healthy cross-matched controls [GIV]. All groups were subjected to complete clinical assessment and routine laboratory investigations. Portal vein diameter, velocity and congestion index [CI] were assessed by Doppler ultrasound. The results showed no significant difference between SBP patients and ascitic patients without SBP as regard PV diameter, velocity or CI. Portal vein diameter was significantly wider in patients with SBP [14.9 +/- 2.08 mm] and cirrhotic ascites [14.15 +/- 2.3] than normal persons [10.5 +/- 2.24 mm] or cirrhotic compensated patients [13.15 +/- 1.6mm]. The mean velocity of PV was significantly lower in patients with SBP [10.4 +/- 2.11] and ascites [10.7 +/- 2.22] than normal persons [15.35 +/- 2.08] or cirrhotic compensated patients [14 +/- 2.6], with no significant difference between controls and cirrhotic compensated patients. The CI of PV was significantly higher in patients with SBP [0.1825 +/- 0.036] and ascites [0.1743 +/- 0.051] than controls [0.05 +/- 0.050] or cirrhotic compensated patients [0.0955 +/- 0.091]. Cirrhotic compensated patients showed significantly wider PV [13.15 +/- 1.6] and higher congestion index [0.0955 +/- 0.091] than normal persons [10.55 +/- 2.24 and 0.05 +/- 0.050 respectively]

Acceptability of the Norplant subdermal implants

Three hundred and forty four women selected to evaluated the acceptability of Norplant. Changes in the menstrual pattern were the most frequent side effects reported. However, such changes diminished with time and by the end of 12 months after insertion 78.1% of users experienced no change in cycle length and about 85% considered their menstrual pattern to be normal.The continuation rate was 86.33% and the pregnancy rate was 0.29/100 w.y reflecting a high continuation rate and good effectiveness