RESUMEN
Objective: Oximes are important materials in organic chemistry. Synparamethyl benzaldehyde oxime [toloaldoxime] is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female Balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs
Materials and Methods: In experimental study, we studied the effects of toloaldoxime on ovary growth and gonadal hormones of neonatal and adult Balb/c mice. A regression model for prediction was presented
Results: The effects of toloaldoxime on neonatal mice were more than adult mice. The greatest effect was on the number of Graafian follicles [59.6% in adult mice and 31.83% in neonatal mice]. The least effect was on ovary weight, and blood serum levels of follicle stimulating hormone [FSH] and luteinizing hormone [LH]
Conclusion: According to the data obtained, toloaldoxime can be considered an anti-pregnancy substance