[Evaluation of relationship between jaw and facial pains with Ischemic heart disease]

Heart disease is the great health problem in different countries .the most important symptom of heart disease with atherosclerosis in chest pain .pain diffuse to the right or left arm, neck and lower jaw. Patients that have central atherosclerosis heart disease with angina in rare cases have a current pain to lower jaw or tooth. The aim this study to determine the frequency of correlation between craniofacial pain and ischemic heart disease. In this descriptive - cross sectional study 210 specimens with ischemic heart disease [pectoris angina and myocardial infarction] that their disease accepted by cardiologist have been selected from Isfahan Chamran and Alzahra hospital in 2009-2010. clinical examination and radiographic evaluation to detect the synchronism of myofacial pain with heart pain were done and the obtained data were analyzed with chi square test. 58/6% of specimens were male and 41/1% of them were female. The age average of specimens were 56/74. 24 of specimens explained that during the MI or angina attack they had jaws pain, after the evaluation the mouth cavity and craniofacial zone with radiographic analyzed and clinical examination no craniofacial or dental problem were detected. From 24 patient with jaws pain 17 patients were male and 7 patients were female and their age average were 54/45. Any of the patients explained the jaws pain as the sole symptom of ischemic heart disease but 24 patients have jaw pain with other symptoms in other parth of the body. so dentist in patient with jaws pain and with no symptom of craniofacial pain to be questions about ischemic heart disease and their symptoms and when dentist distrust to patient then refer him to cardiologist

Rubinstein-Taybi Syndrome; a case report

Rubinstein-Taybi Syndrome is a rare genetic disorder with characteristic features including downward slanting palpebral fissures, broad thumbs and halluces, and mental retardation. Systemic features may involve cardiac, auditory, ophthalmic, endocrine, nervous, renal and respiratory systems. This syndromeis sporadic in nature and has been linked to microdeletion at 16p 13.3 encoding CREB-binding protein gene [CREBBP]. We report a 15-years-old girl, a known case of chronic renal failure, with downward slanting palpebral fissures towardthe ears, hypertelorism, short stature, beaked nose, micrognathia, strabismus, dental anomalies, large toes, broad thumbs, and mental retardation

case report of a 2.5-year-old girl with angelman syndrome [AS]

Angelman Syndrome [AS] is a genetically determined syndrome that has a unique behavioral phenotype. This syndrome is described as jerky ataxia and an unusual happy facial expression with pathological laughter. Severe mental retardation is a unique feature of the syndrome, together with microbrachycephaly and abnormal electroencephalographic findings with or without clinical seizures. The patients cannot speak or at most, they have a vocabulary consisting only of a few words. The genetic abnormality of AS has been located on chromosome 15q11-q13. Patients with As mostly have deletions on the maternally derived allele [75-80%] while some of them show paternal uniparental disomy [approximetly sign 2%] or a rare imprinting mutation developmental disorder caused by deletion of the maternally-inherited chromosome 15q11-13. A 2.5-year-old girl is presented. Clinical suspicion of AS was raised at the age of 27 months when she presented with mental retardation and epilepsy, absence of speech, inability to gait and paroxysmal episodes of laughter. Moreover, she had facial dysmorphic features such as microbrachycephaly, mid-facial hypoplasia, macrostomia and a prominent mandible. Chromosomal analysis revealed 46 xx with the deletion of 15q chromosome [15q11q13-snrpn/ic] Our patient met the classical phenotype and genotype of AS