RESUMEN
Endocrine disorders account for a significant amount of the global burden of disease. Hospital-based data provide substantial insight into the patterns of disease at community level to bridge the gaps in literature about the epidemiology of specific endocrine disorders, to aid in early diagnosis and identify priority areas for resource allocation. Methods: It was a cross sectional study conducted in the Department of Biochemistry, MGIMS, Sevagram. Secondary data analysis of Electronic Medical Records spanning over the years 2016 and 2017 was done. Results: A total of 1739 patients, 702 in 2016 and 1037 in 2017 were included in which substantially more investigations were ordered for females in OPD whereas in IPD, more tests were ordered for male patients. Conclusion: This study helps us gain an insight into the trends followed by some endocrine abnormalities in patients of a tertiary care centre in Central India. They throw light upon the burden of disease on the community that our focus during screening for early diagnosis as well as while formulating policies should be these hormones.
RESUMEN
A prospective cohort study was carried out to evaluate the role of early second trimester high sensitivity C - reactive protein for prediction of adverse pregnancy outcomes. Total 150 early second trimester primigravidae were analyzed for serum hsCRP level which was measured by immunoturbidimetry assay and followed till delivery. A statistically significant correlation was found between elevated serum hsCRP concentrations in early second trimester primigravidae and adverse pregnancy outcomes like preterm delivery and pregnancy induce hypertension (p<0.001). This study reveals that elevated serum hsCRP concentration observed in early second trimester primigravida could help to predict adverse maternal and fetal outcomes and if timely preventive prophylactic therapies are tried, would help to prevent morbidity and mortality due to pregnancy disorders.