RESUMEN
Forty patients with head injuries in Ain-Shams University Hospitals were subjected to this study to find out whether an early and initial determination of coagulation state is of value for affecting the outcome of such cases with head injuries. The prothrombin time [PT], activated thromboplastin time [a PTT], fibrinogen degradation products [FDP] and blood platelets were measured 7 hours after admission to pick up the high risk patients. The coagulation profile were measured again after 3 and 7 days to detect the occurrence of any coagulopathy changes and its relationship with patient's outcome. It is concluded that the coagulopathy which is present in patients with head trauma appears to be correlated with poor survival. The study offers recommendation to investigate for coagulopathy in head injured patients and to be carefully managed. Fresh frozen plasma must be a routine treatment on admission instead of whole fresh blood transfusion to protect against the increase in blood pressure and to protect against DIC syndrome