RESUMEN
Because there are not related to synthetic insulin types and their specific use in canine studies in Chile, it became a literature review of the insulins present in Chile most used in dogs, to analyze and discuss data on insulin therapy diabetes mellitus, deepening mainly in the disease either both in its etiology, and epidemiology in our country, which was demonstrated through characterization incidence of canine patients with endocrine diseases at the Veterinary Hospital of the University of Chile between 2012 and 2015. Given the importance of this disease in human endocrinology, it is that studying the effects of various insulins in dogs, can generate an appropriate model level research pharmacokinetics and pharmacodynamics of insulins available in our country, which constitutes the canine model as a suitablemodel of study for human medicine, and generate future scientific research.