RESUMEN
Lead poisoning can present with nonspecific signs and symptoms such as abdominal pain, constipation, irritability, difficulty concentrating, and anemia. A 57-years-old man admitted to the hospital due to abdominal pain of 40 days duration and 9 kg of weight loss. He had addiction to the oral opium from years ago. He had anemia and jaundice in physical exam .His abdominal pain was after eating and we evaluated upper and lower parts of gastrointestinal and we didn't find any clue. All of the other imagings incuding,small bowel follow through,abdominal C.T. angiography and magnetic resonance enterography were normal. Finally,serum lead levels were measured and were 1961 mic/ dl [normal range of 10 mic/dl] elevated;Therefore established diagnosis was lead poisoning. We reported a patient with lead poisoning that was presented with abdominal pain and abnormal liver biochemistries. Because of his addiction to the oral opium agents and some reports, it seems the most probable source of lead poisoning is oral opium agent