Role of dyslipidemia in old age of both sexes

To observe the risk of dyslipidemia and variation in other biochemical parameters in old age subjects of both sexes and to observe the relationship of biochemical parameters with the dietary pattern. Seventy males and 30 females, with age ranging from 40-60 years were included in the study. Levels of serum triglyceride, cholesterol, uric acid, blood sugar, blood urea and serum creatinine were estimated. The levels of serum triglyceride and uric acid were significantly increased in both sexes. Other biochemical parameters showed no significant difference. The dietary pattern and life style showed a direct relation with the level of triglyceride as compared to that of serum cholesterol. Levels of triglycerides were found to be elevated in older patients. An education program is needed for the dietary modifications and morning walk that may lead to the lowering of serum triglyceride level

Geographical / physiological diversity of female breast cancer among developing and developed countries

To find out geographical/Physiological diversity of female breast cancer among developing and developed countries. Prospective observational study. Cancer Ward and out-patient of Radiotherapy Department, Jinnah Post Graduate Medical Centre, Karachi, Pakistan. Patients: 100 female patients with histologically verified breast cancer. Majority of the patients in this study were middle class housewives. Thirty women were addicted to beetle nuts. None of the patients had family history of breast cancer. Fifty-one developed cancer in right breast and forty-nine in the left breast and it was seen common in 4th and 5th decade. 70% hod Intra ductal carcinoma and 27% had invasive ductal carcinoma. 25 patients had breast cancer since three years while 72 had it for the last four five months. ESR status was positive in 70 patients and negative in 30 patients. Seventy-five percent of breast cancer occurs in Pakistani women with no recognized major risk factor. Further research is needed on the population of different cities of Pakistan to find the actual risk factor responsible for the disease