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1.
Pakistan Journal of Medical Sciences. 2016; 32 (1): 101-105
en Inglés | IMEMR | ID: emr-178584

RESUMEN

Objective: To investigate the outcome of rhegmatogenous retinal detachment repair at Vitreoretinal unit of Jinnah Post Graduate Medical Centre Karachi in year 2014


Methods: One hundred and three eyes of one hundred and three patients, who underwent three ports parsplana vitrectomy + band + silicone oil, three ports pars plana vitrectomy + silicone oil, three ports pars plana vitrectomy + C3F8 for rhegmatogenous retinal detachment [RRD] repair, at Jinnah Post Graduate Medical Centre, were included in this observational prospective study. Parsplana vitrectomy was done using 23G vitrectomy system. Duration of study was one year. Removal of silicone oil [ROSO] was done on the basis of completely flat retina at least for eight weeks or because of complications due to silicone oil. Patients were followed up post operatively on day one and after one week and then at four weekly interval till the end of the study


Results: Anatomical success was achieved in 91 eyes [88.3%]. However in 12 eyes [11.7%] retina redetached after removal of silicone oil. Functional success achievement of visual acuity of 3/60 or better was achieved in 85 [82.5%] of eyes post operatively after removal of silicone oil or absorption of gas C3F8 as the case may be


Conclusion: Re-detachment is common after removal of silicone oil and incidence of re-detachment is related to the degree of preoperative PVR and location of breaks. Re-detachment occurs more commonly if the breaks are inferiorly located as compared to the superior ones

2.
Pakistan Journal of Medical Sciences. 2015; 31 (4): 895-898
en Inglés | IMEMR | ID: emr-170009

RESUMEN

To analyze the frequency of hepatitis B and C in patients undergoing cataract surgery. This descriptive study was conducted at department of Ophthalmology Jinnah Post Graduate Medical Centre. The duration of study was seven months from May 2013 to November 2013. After taking informed consent from the patient and hospital ethical committee all patients presenting with cataract and undergoing cataract surgery were evaluated for the existence of hepatitis C and B. Diagnosis of hepatitis C or B was made on the criteria that a patient must be positive for either Anti-HCV or HBsAg or both. Proformas were filled and data was collected and analysis was done. Pearson's correlation coefficients were calculated to calculate the occurrence of hepatitis C and B in general population undergoing cataract surgery. Six hundred and forty-eight patients were operated on for cataract surgery at Jinnah Post Graduate Medical Centre during the study period. Mean age of patients was 63 years, 300 [46.29%] were male and 348 [53.70%] female. Out of them 57 [8.79%] patients were carriers of either Hepatitis C or B. Hepatitis B accounted for 17 cases [2.62%] however Hepatitis C positive were 40 cases [6.17%]. Nobody was simultaneously affected by both hepatitis C and B. Significant number of asymptomatic carriers of hepatitis C and B were found in preoperative cataract patients. It is recommended that preoperative screening of all cataract patients should be done so that asymptomatic carriers might not become a threat for spread of disease

3.
Pakistan Journal of Medical Sciences. 2014; 30 (6): 1383-1387
en Inglés | IMEMR | ID: emr-148801

RESUMEN

To assess the effectiveness of intravitreal injection of Bevacizumab in the treatment of diabetic macular edema. This case series was conducted at Department of Ophthalmology, Jinnah Post Graduate Medical Centre [JPMC], Karachi. The duration of study was six months from May 26, 2011 to November 25, 2011. The study group comprised of 54 patients of the Diabetic Macular Edema [DME]. Intravitreal injection of 1.25 mg of bevacizumab [Avastin] was injected 3.5 mm from the limbus under topical anaesthetic drops. Post procedure follow up was scheduled on 1[st] post procedure day and after one month. Post procedure Optical Coherence tomography [OCT] was performed in all patients 1 week before and 1[st] month after 1[st] injection. The results were statistically analyzed through SPSS 17. Out of the 54 Eyes of 54 Patients who were given the Intravitreal injection of Avastin [Bevacizumab], 43 Eyes [79.6%] showed more than ten percent decrease in macular thickness from pre-injection thickness, 10 Eyes [18.5%] showed less than ten percent decrease and 1 Eye [1.9%] showed increase in macular thickness post operatively after one month. Intravitreal injection of Bevacizumab [Avastin] is effective in the treatment of diabetic macular edema


Asunto(s)
Humanos , Masculino , Femenino , Anticuerpos Monoclonales Humanizados , Inyecciones Intravítreas , Diabetes Mellitus , Factor A de Crecimiento Endotelial Vascular , Diabetes Mellitus Tipo 2 , Diabetes Mellitus Tipo 1
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