Johanson-blizzarci syndrome with diamond-blackfan anemia

Johanson Blizzard syndrome [JBS] is a rare multi-system disorder characterized by congenital aplasia or hypoplasia of alae nasi, exocrine pancreatic insufficiency, hypothyroidism, deafness, growth retardation, varying degree of mental retardation, alopecia, wide open fontanels, anti-mongoloid slant, cafe-au-lait spots and absent of permanent teeth. We report a 3 months old male child having Johanson Blizzard syndrome with classical clinical features, pancreatic insufficiency and Diamond-Blackfan anemia

Current practice of doctors regarding the diagnosis and use of antibiotics in enteric fever in children: knowledge, attitude and practice

The objectives were to know current practice and knowledge of doctors regarding the diagnosis and use of antibiotics in Enteric Fever in children. The study was conducted in Lahore-city. It was a descriptive, epidemiological study. 150 doctors participated in the study. 51% were MBBS, 33% were postgraduate trainees and 16% had postgraduate degrees. Ciprofloxacin was prescribed as first choice by 51% and second choice by 37.8%. Ofloxacin was advised as first line by 21% doctors and injection Ceftriaxone by 18.6%. Chloramphenicol was advised by 8% doctors. Only 67.3% doctors prescribed the antibiotics for recommended duration. 62% doctors did not know the dosage in children. Second line antibiotics are used irrationally and those are prescribed for less than recommended duration, which leads to multi-drug resistance and relapse of fever

Knowledge and practices of the medical practitioners about management of childhood tuberculosis, Gujrat City

The objective was to describe current practices and knowledge of medical practitioners about management of childhood tuberculosis. The study was conducted in Gujrat city. It was a descriptive, epidemiological study. A sample size of 248 Doctors was obtained who were interviewed with the help of semi-structured questionnaire. Final data was analyzed with the help of EPI - INFO Computer Program. The results showed that for diagnosis of tuberculosis in children using Kenneth Jone's Criteria, only 33% of medical practitioners answered correctly. Thirty two percent of the doctors knew the correct regimen for treatment of childhood tuberculosis. About 63% doctors know at least partially the guidelines of tuberculosis management and 3% of the doctors practicing did not know and never heard about the guidelines for tuberculosis management. Majority of the doctors answered correctly about the symptoms and signs, only 39% gave advice for regular and complete course. It was concluded that knowledge among medical practitioners regarding management of childhood tuberculosis is lacking. Due to poor knowledge about the treatment regimens it is essential to update their knowledge by attending the workshops/seminars/conferences / short courses and by reading the new guidelines for management of childhood tuberculosis

Co-relation of birth weight with periventricular hemorrhage-a prospective study of two groups of newborns

To determine the difference between prevalence of Periventricular - Intraventricular Hemorrhage [PIVH] in the newborns on the basis of birth weight. Prospective study. Neonatology Unit, Department of Paediatrics, Post Graduate Medical Institute / Services Hospital, Lahore, from 1[st] April to 31[st] July 2000. All new born admitted in Neonatal Unit of Services Hospital within 24 hours of birth were included in the study. Birth weight was documented. Cranial ultrasonography was done twice in all babies, once within 24 hours of birth and second between 4 and 5 days of life. All newborns included in the study were divided into two groups on the basis of birth weight; One group with birth weight less than 1500 gms the second group with weight 1500 gm and more. In babies with PIVH, the extent of hemorrhage was graded. 364 out of 448 [81%] fulfilled criteria for admission to this study. Cranial ultrasound was done twice in all babies, irrespective of diagnosis. 36 babies [9.9%] died within 72 hours of life. Babies with birth weight less than 1500 gm were 110 [30%], whereas, those more than 1500 Gm birth weight it was 68 [62%], 54 [21%] babies were delivered at Services Hospital, 79 [22%] in different maternity centers and 169 [46%] were home delivered. Distribution of grading of PIVH showed that 64 cases had grade-l hemorrhage, 27 had grade-ll, 18 had grade-Ill and 13 had Grade-IV hemorrhage. First scan detected 55 [45%] cases. Cranial ultrasound should be done in all premature and low birth weight newborns within 4-5 days of life to detect PIVH fairly accurate and easily.Co-relation of birth weight with periventricular hemorrhage