Bone mineral density of the spine and femur in United Arab Emirates women: relation to anthropometric, reproductive, and lifestyle factors

Establish normative data for bone mineral density [BMD] at the spine and femur in healthy United Arab Emirates [UAE] women, compare BMD of UAE women to other populations, and examine the relationship of BMD to anthropometric, reproductive, and lifestyle factors. Three hundred and one healthy UAE women volunteers aged 20-79 years were interviewed and studied hr measurements of height, weight, body composition using bioelectric impedance, handgrip strength, aid axial BMD using dual energy x-ray absorptiometry. Mean values for BMD of UAE women were compared to those of other Arabian Gulf women and to US/European Caucasian women. Mean standardized BMD of UAE women showed the expected decline with age after reaching its peak in the 4th decade for the spine and the fifth decade for the total femur Mean spine BMD was significantly lower than US/European Caucasian women across all age decades. Mean total femur BMD was significantly higher than US European Caucasian women, except in the 3rd decade, where it women significantly lower Peak standardized BMD [age range 20-39 years] of spine was significantly lower than the reference range for US European Caucasian women [-0.54 SD, P<0.01], however peck standardized BMD of total femur was not significantly different. There were significant positive correlations between BMD, and weight, body mass index, free fat mass, percent body fat, handgrip strength, and walking duration. There were significant negative correlations between BMD, and age, poor health, sears post menopause, number of pregnancies, and beast-feeding duration [p<0.05/or all comparisons]. Multiple regression analyses showed that age, weight, handgrip strength and number of pregnancies were significant predictors of spine BMD whereas weight, menopausal duration, and walking duration were significant predictors of total femur BMD. We have provided a database of BMD of the lumbar spine and total femur for healthy UAE women Aged 20-79 years and showed that UAE women, like other Arabian women, have louver peak BMD of the spine compared with US/European Caucasian women. We have also demonstrated that multiparity, physical activity and weight are significant predictors of BMD in this population. These factors should be the subject of public health interventions to prevent osteoporosis

Contributions of sunshine deprivation and maternal vitamin D deficiency to rickets in the United Arab Emirates

The aims were to better characterize the clinical and biochemical features of rickets and to asses the contributions of sunshine deprivation to maternal vitamin D status and thus its relation to rickets in the child. The clinical and biochemical characteristics of 40 consecutive rachitic children and the sunshine exposure and vitamin L] status of their mothers at Al-Ain, United Arab Emirates' were studied. Rachitic children had significant skeletal deformities, growth and motor developmental delay and all had vitamin D deficiency. Clinical features' of children with "moderate/severe" vitamin D deficiency [serum 25-OHD 12.5-37.5 nmol/L] were similar to those with "very severe" vitamin D deficiency [

Bone mineral density of the spine and femur in United Emirates women: relation to anthropometric, reproductive, and lifestyle factors

Establish normative data for bone mineral density [BMD] at the spine and femur in healthy United Arab Emirates [UAE] women, compare BMD of UAE women to other populations, and examine the relationship of BMD to anthropometric, reproductive, and lifestyle factors. Three hundred and one healthy UAE women volunteers aged 20-79 years were interviewed and studied by measurements of height, weight, body composition using bioelectric impedance, handgrip strength, and axial BMD using dual energy x-ray absorptiometry. Mean values for BMD of UAE women were compared to those of other Arabian Gulf women and to US/European Caucasian women. Mean standardized BMD of UAE women showed the expected decline with age after reaching its peak in the 4th decade for the spine and the fifth decade for the total femur Mean spine BMD was significantly lower than US/European Caucasian women across all age decades. Mean total femur BMD was significantly higher than US/European Caucasian women, except in the 3rd decade, where it was significantly lower peak standardized BMD [age range 20-39 years] of spine was significantly lower, than the reference range for US/European Caucasian women [-0.54 SD, P< 0.01]; however, peak standardized BMD of total femur was not significantly different. There were significant positive correlations between BMD, and weight, body mass index, free fat mass, percent body fat, handgrip strength, and walking duration. There were significant negative correlations between BMD, and age, poor health, years post menopause, number of pregnancies, and breast-feeding duration [P<0.05 for all comparisons]. Multiple regression analyses showed that age, weight, handgrip strength and number of pregnancies were significant predictors of spine BMD whereas weight, menopausal duration, and walking duration were significant predictors of total femur BMD. We have provided a database of BMD of the lumbar spine and total femur for healthy UAE women aged 20-79 years, and showed that UAE women, like other Arabian women, have lower peak BMD of the spine compared with US European Caucasian women. We have also demonstrated that multiparity, physical activity and weight are significant predictors of BMD in this population. These factors should be the subject of public health interventions to prevent osteoporosis

Contributions of sunshine deprivation and m aternal vitamin Ddeficien cy to rickets in the United Arab Emirates

The aims were to better characterize the clinical and biochemical features of rickets and to asses the contributions of sunshine deprivation to maternal vitamin D status and thus its relation to rickets in the child. The clinical and biochemical characteristics of 40 consecutive rachitic children and the sunshine exposure and vitamin D status of their mothers at Al-Ain United Arab Emirates were studied. Rachitic children had significant skeletal deformities, growth and motor developmental delay: and all had vitamin D deficiency. Clinical features of children with "moderate/severe" vitamin D deficiency [serum 25 OHD 12.5-37.5 nmol/L] were similar to those with "very severe" vitamin D deficiency [<12.5 nmol/L]. The median serum alkaline phosphatase concentration was higher in the latter Sixteen mothers [40%] had "very severe" vitamin D deficiency and 68° were not exposed to sunlight. Maternal body surface area exposed to sunlight correlated with serum 25-OHD concentration [r=0.48, P=0.002]. Rickets was mainly due to severe vitamin D deficiency rickets. Maternal vitamin D deficiency due to sun shine deprivation may contribute to persistence of rickets. Maternal sunshine exposure that ensures adequate vitamin D status should he emphasized in the strategies to eliminate rickets