RESUMEN
A leiomyoma is a remarkably rare cause of a benign, one-side tonsillar enlargement. The diagnosis is essentially histologic and will not normally be suspected clinically. Immunohistochemistry is needed for substantiation of the morphology and confirmation. We submit this illustrative case report.
RESUMEN
Primary hepatic mucosa-associated lymphoid tissue lymphoma (MALToma) is a rare entity. Its coexistence with other malignancies is even rarer. Only few case reports of its association with other malignancies mostly gastric and colon cancer have been published. We report a case of primary MALToma of liver in an unusual setting of dual solid malignancy.
RESUMEN
Benzoate hydroxylation test revealed that Cu(II) reacting with H2O2 produced OH degree radicals, which nicked or damaged DNA or hydroxylated benzoate, the extent of damage or hydroxylation depending on the period of incubation. The production of OH degree free radicals was also supported by the scavenger studies. Neither Cu(II) nor H2O2 alone could damage DNA or hydroxylate benzoate. EDTA-chelated Cu(II) plus H2O2 could damage DNA or hydroxylate benzoate only in presence of the biological reductant, L-cysteine, the damage increased with the increasing molar ratio of L-cysteine to Cu-EDTA. The biological relevance of the EDTA chelated Cu(II) and H2O2 system is discussed.
Asunto(s)
Benzoatos/química , Ácido Benzoico , Quelantes , Cobre , Daño del ADN , Peróxido de Hidrógeno/química , Oxidación-ReducciónRESUMEN
Nitrofurantoin caused a dose dependent inhibition of growth and decrease in viability of V. cholerae cells, the 10% (D10) and 37% (D37) survival doses being 50 and 19 micrograms/ml respectively. The drug at a concentration of 60 micrograms/ml caused 86% inhibition of DNA synthesis. Both light and electron microscopic observations revealed that treatment with nitrofurantoin (60 micrograms/ml for 1 hr at 37 degrees C) led to a significant filamentation of the V. cholerae cells, ultrastructure of the cell cytoplasm, plasma membrane and cell wall however remaining unaltered from those of untreated cells. The results are discussed in relation to DNA lesions produced by and the carcinogenic potential of the drug.