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Aim: To identify the quantitative trait loci (QTLs) associated with various morphological and physiological traits. Methodology: A recombinant inbred line (RIL) population of wheat (Triticum aestivum L.) derived from cross of heat tolerant parent WH1021 with heat sensitive parent WH711 was used. For creation of heat stress delay in sowing (four weeks) was done in late sown from timely sown. Days to heading, days to maturity, plant height along with physiological traits viz. photosynthetic rate, transpiration rate, intrinsic water use efficiency (iWUE) and normalized difference vegetative index (NDVI) were recorded in both timely and late sown conditions over two years. Results: A linkage map consisting of 22 SSR was prepared covering eleven chromosome of wheat. Using the software WinQTL cartographer version 2.5, significant genomic regions associated with heat tolerance were observed on 2A, 2D, 4A and 5A chromosomes with composite interval mapping. QTLs for photosynthetic rate were found consistently for both years on chromosome 2D. In present study, significant variation was reported for days to heading and its QTLs were identified on chromosome 2A and 2D. Interpretation: The QTLs obtained for physiological and morphological traits in wheat can be used for marker-assisted selection for heat tolerance in wheat
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BACKGROUND AND PURPOSE: A better understanding of appropriate sequencing and use of multimodality approach in the management and subsequent improvement in overall survival mandates a vigil on quality of life issues. Intensity modulated radiotherapy (IMRT) is a powerful tool, which might go a long way in reducing radiation doses to critical structures and thereby reduce long term morbidities. The purpose of this paper is to evaluate the impact of IMRT in reducing the dose to the critical normal tissues while maintaining the desired dose to the volume of interest for abdominal malignancies. MATERIALS AND METHODS: During the period January 2002 to March 2004, 11 patients of various sites of malignancies in the abdominal region were treated using physical intensity modulator based IMRT. Plans of these patients treated with IMRT were analyzed using dose volume histograms. RESULTS: An average dose reduction of the mean values by 50% to the liver, 57% to the right kidney, 56% to the left kidney, 66% to the cord and 27% to the bowel, with respect to the GTV could be achieved with IMRT. The two-year disease free survival was 79% and two-year overall survival was 88%. The average number of IMRT fields used was six. CONCLUSION: IMRT with inverse planning enabled us to achieve desired dose distribution, due to its ability to provide sharp dose gradients at the junction of tumor and the adjacent critical organs.