Transient synovitis of hip joint following COVID-19 infection in a child with Hodgkins lymphoma

Transient synovitis is a common cause of hip pain in children. COVID-19 pandemic affected pediatric cancer patients more often that general pediatric population. COVID-19 has been associated with various musculoskeletal symptoms including synovitis. Radiological assessment of these symptoms can contribute significantly in management of such patients. We report a case of transient synovitis of hip joint following COVID-19 infection in a 10-year-old boy with Hodgkins抯 lymphoma. He presented with fever and myalgia, found to be positive for COVID-19, managed conservatively. Two weeks later presented with right hip pain and limping. He was found to have restricted joint mobility and hip tenderness. Magnetic resonance imaging (MRI) pelvis was done which showed minimal right hip effusion and synovial thickening and enhancement. He was managed conservatively and recovered completely.

Clinical Correlation of Maximum Standardised Uptake Value (SUVmax) in Positron Emission Tomography- Computed Tomography (PET-CT) with Initial Disease Staging of Carcinoma Breast- An Observational Study at Indian Tertiary Care Centre

The most common primary malignant disease in the world amongst women is carcinoma breast. Metabolic activity of a lesion (SUVmax) has strong clinical correlation with various prognostic factors according to numerous literature reviews. The main aim of this study is to assess the correlation between maximum Standardized Uptake Value [SUVmax] and initial disease staging (as per AJCC TNM-8th edition). We wanted to study the correlation between metabolic activity [SUVmax] of the primary tumour in breast carcinoma, and size of the primary, nodal and distant metastatic status.METHODSThis is an observational study conducted over a period of two years in breast cancer patients [n=139] undergoing PET-CT as a part of initial staging. PET-CT was done using Siemens Horizon True-V PET according to institutional protocols.RESULTSSignificantly higher SUVmax values were observed in tumours with larger size [>2 cms]. However, there was no significant correlation between SUVmax of primary tumours and the status of axillary nodal involvement and distant metastases [p = 0.125 and 0.847 respectively].CONCLUSIONSMetabolic activity of primary breast cancer has strong clinical correlation with size; however, there is no such correlation found in nodal and metastatic spread of the disease.