RESUMEN
Medications that reduce gastric acid secretion are commonly prescribed for treating gastroesophageal reflux disease. However,several studies have shown that these medications are not very effective, and are associated with adverse effects. This articlediscusses the physiology of gastric acid secretion, clinical indications and pharmacology of acid suppressing medications, andpossible adverse effects of these medications
RESUMEN
This prospective observational study on 36 neonates aimed to estimate the correlation between the new Saturation Oxygen distending Pressure Index (SOPI) and Oxygenation index. SOPI had high correlation (r=0.94) with oxygenation index. SOPI of <2, 2, and 3.7 represented mild, moderate and severe pulmonary disease, respectively with high sensitivity and specificity.