Congenital pyloric atresia [CPA]: report of two cases, with review of literature

We are reporting two neonates with isolated pyloric atresia, with an objective to emphasize the importance of considering this rare condition in the differential diagnosis of upper intestinal atresias. Both had non-bilious vomiting and epigastric fullness. X-ray showed a dilated gastric shadow with no evidence of gas in the rest of the abdomen. On exploration they had pyloric atresia which was corrected with gastroduodenostomy. Congenital pyloric atresia is a rare condition, which presents with features of gastric outlet obstruction. It can be diagnosed antenatally but the picture can mimic other conditions. Epidermolysis bullosa has a strong association with it and require skin biopsy for diagnosis

Megacystis-microcolon-intestinal hypoperistalsis syndrome - report of a very rare pathology in a neonate

We are reporting a baby who presented with features of neonatal intestinal obstruction, with an x-ray picture suggestive of hold up at the duodenal level. On laparotomy he had malrotation of the gut which was corrected. He also had a dilated urinary bladder, which later on was treated with vasicostomy. The baby did not move his bowel inspite of no mechanical obstruction and even bypass procedure [gastrojejunostomy]. She had all the features of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome [MMIHS]. MMIHS [also called hollow viscus myopathy] is a neonatal condition causing a severe form of pseudo [functional] intestinal obstruction. This is an autosomal recessive disorder more common in females. The various components of the syndrome are dilated urinary bladder, decreased motility of the gut, microcolon, intestinal malrotation and lax abdominal musculature. All these components of the syndrome were found in our case