RESUMEN
Background and Objective: Iron oxide nanoparticles, including nanoparticles is important in industry and medicine. Nanoparticles affect on detoxification of environmental pollutants such as Pesticides and chlorinated organic solvents.This study was done to evaluate the short term effect of Fe2NiO4 composite nanoparticle on kidney function indeces in wistar rats
Methods: In this experimental study, Twenty four Wistar rat were randomly allocated into three groups, including: control, treated groups 1 and 2. Animales in control, treated groups 1 and 2 were received 0.5cc of saline, 0.5cc of solution containing 100, 200 ppm Fe2NiO4 for 7 days, respectively. Uric acid, ceratinine and urea [BUN] were measured at day 2, 7 and 14
Results: BUN level in treated groups 1 and 2 significantly reduced in comparison with control group at day 7, 14 after intervention [P<0.05]. Uric acid level in treated groups 1 and 2 significantly increased at day 7 and 14. 2 week after intervention, the mean creatinine levels in treated group 2 group significantly reduced in compare to the in treated group 1 and controls [P<0.05]
Conclusion: It seems that the application of Fe2NiO4 nanoparticles in biological system has no toxic effect on the kidney function indeces
RESUMEN
Resin composites are a common type of tooth coloured restorative materials. These materials are brittle and their major shortcomings are sensitivity to flaws and defects, low tensile strength, and susceptibility to catastrophic failure.The role of home bleaching agents on the fracture toughness of resin composites using four-point bending test is scanty.To compare the fracture toughness K[Ic] of resin composites on a four-point bending test and to assess the effect of distilled water and a home bleaching agent on the resistance of the materials to fracture. seventy-two bar-shaped specimens were prepared from three materials: Rok [SDI], Estelite [Tokuyama], and Vit-l-escence [Ultradent] and divided into three groups.Two groups were assigned as [control] and conditioned in distilled water at 37 degrees Celsius for 24 hours or 21 days, respectively. The specimens in the third group [treatment] were stored in distilled water for 21 days and bleached using Polanight [SDI] for 2 hours daily. For each material, a total of 24 disc-shaped specimens were prepared and after each time interval loaded in a four-point bending test using a universal testing machine with a crosshead speed of 0.5 mm/m. The maximum load to specimen failure was recorded and the K[Ic] was calculated. Statistical analysis using two-way ANOVA showed a significant relationship between materials and treatment [P<0.05]. Tukey's test showed that after 24 hours of immersion in distilled water, K[Ic] was not significantly different between materials; Rok revealed the highest value followed by Estelite and Vit-l-escence. The bleaching agent significantly decreased the K[Ic] values of Estelite and Rok while it did not affect that of Vita-l-escence. Immersion in distilled water for all resin composites caused a significant decrease in K[Ic]. The fracture toughness of the resin composites was affected by the bleaching agent and 21day immersion in distilled water