RESUMEN
The aim of this study is to evaluate the efficacity of immunosuppressive therapy in steroid - resistant idiopathic nephrotic syndrome. 30 children present to the renal biopsy a focal and segmental glomerulosclerosis [HSF 18 cases], minimal change disease [LGM: 9 cases] and diffuse mesangial proliferation [PMD: 3 cases]. 9 of 11 patients did not respond to cyclophosphamid. 28 patients received the cyclosporine - prednisone combinaison with a cyclosensibility in 23 patients [80 per cent]. The mycophenolate mofetil [MMF] was used in 7 patients, and 3 were in remission. In this study 7 patients [23 per cent] develop a chronic renal failure. the cyclophosphamid has not beneficial effects. The cyclosporine is an effective therapeutic agent. MMF has emerged as an important new therapeutic option for the treatment of SNCR and HSF
Asunto(s)
Humanos , Masculino , Femenino , Síndrome Nefrótico/congénito , Nefrosis/etiología , Niño , Nefrosis/tratamiento farmacológico , Inmunosupresores , Esteroides , Resistencia a Medicamentos , Ciclofosfamida , Ciclosporina , Ácido Micofenólico/análogos & derivados , Glomeruloesclerosis Focal y SegmentariaRESUMEN
Solitary fibrous tumors are mescenchymal neoplasms which develop from connective tissue. They rarely occur in the kidney and to our knowledge only 11 cases have been reported in the literature so far. We herein report a solitary fibrous tumor of the Kidney in a 60-year-old patient presenting with renal colic. CT scan revealed a tumor in the renal hilum. The patient was subjected to total nephrectomy, and histological examination of the excised tissue showed fusiform cellular fibrotic proliferation. Immunohistochemistry confirmed the diagnosis by showing positive CD 34 and bcl-2 markers