Cerebral palsy: clinico-radiological correlation

Twenty one children with spastic cerebral palsy [CP] were examined with cranial CT. In 15 cases [71.4%], the CT findings were abnormal. The most frequent finding was brain atropy [53.3%]. Patients with CP of postnatal anoxia more often had pathological CT lesions than patients with other causes. CT changes were more in patients with epilepsy than in patients without. Cerebral infarction and atrophy were more frequent in patients with hemiplegia than in patients with other type of spastic cp

Incidence of candida species in thrush stomatitis and their sensitivity to new antifungal drugs

Oral thrush is one of the commonest mycosis in health as well as in debilitated infants and children, especially in those receiving antibiotics or immunosuppressive drugs. Candida albicans is the commonest causative agent. Treatment of this infection is still difficult. Recently, several antifungal drugs were introduced, which were studied on 300 patients in the age group of birth up to 5 years with thrush stomatitis. From each patient, two swabs were obtained; one for culture of Candida species and the other for microscopic examiniation for the presence of yeast cells. The isolated yeast colonies were further identified. One hundred strains of candida isolated from cases with thrush stomatitis were tested for their sensitivity to six antifungal drugs using the disc diffusion method. Although nystatin was proved to be the drug of choice, yet it is only for topical use. So, other systemic drugs should be given