[Central serous chorioretinopathy: clinical, fluorescrin angiography and optical coherence tomography findings]

To investigate different forms of central serous chorioretinopathy [CSC] with angiography and Optical Coherence Tomography [OCT]. In a retrospective study, 8 eyes of 8 patients [7 men, and I women; mean age: 37 years] with central serous chorioretinopathy were examined with angiography and Optical coherence tomography. Mean follow-up was 36 months. Clinically all patients demonstrated unilateral typical CSC syndrome. In the acute phase; fluorescein angiography shows vigorous leakage throughout the base of retinal detachement. Different angiography sights were noted. Area of retinal posterior epithelium damage were noted in 4 cases. OCT showed an increased thickness within the area of CSC in all cases. Although CSC resolves spontaneously. In almost all cases, some factors are associated with reduced visual acuity

[Cone-rod dystrophy: a case report]

Cone-rod dystrophy [CRD] is an inherited retinal dystrophy with initial loss of cone mediated functions followed by rod dystrophy. We report the case a young male affected by CRD. Case report: The case of a 27-year-old male patient is presented. He was hospitalized for decreased vision of both eyes and hemeralopia. The eye fundus examination showed bilateral lesions of retinitis pigmentosa in the supero temporal sector and macular cystoid oedema. Both photopic and scotopic full field ERG amplitudes were reduced, showing involvement of both photoreceptor systems. However, cone response was reduced more than that of rod response suggesting CRD diagnosis. His mother was diagnosed with age-related macular degeneration and his brother with CRD. The patient refused genetic analysis. Based on family history and clinical diagnosis, the disease was classified as cone-rod dystrophy. Discussion and Cone-rod dystrophy [CRD] is a particular form of retinitis pigmentosa [RP] which characteristically lead to early impairment of vision, usually from the first or second decade of life. CRD patients suffer from hemeralopia, loss of visual acuity and peripheral visual fields and show reduced ERG responses. In later life, vision may be reduced to a bare perception of light. Ophthalmoscopic abnormalities in CRD patients ranged from minor granular pigmentary changes in the posterior pole to widespread atrophy. Genetic analysis revealed various mutations in many genes may lead to CRD. There's no treatment available for this condition. Genetic advice is the most effective mean for preventing this inherited disease