Partial hydatidiform mole in Morocco: an epidemiological and clinical study

This retrospective study reviewed cases of partial hydatidiform mole [PHM] diagnosed at the University Hospital in Casablanca from 2000 to 2010 in order to examine the epidemiological, clinical, therapeutic and progressive pathological factors associated with PHM. All PHM cases confirmed clinically and sonographically at pathological examination were included. We identified 24 cases of PHM among 60 748 births and 1704 abortions, giving a frequency of 0.4 per 1000 pregnancies and 1.4% of abortions. The mean age was 26 years [range: 16-55 years]. The circumstances of discovery and clinical ultrasound varied: 79.2% of patients sought consultation for bleeding; clinical thyrotoxicosis syndrome was found in 1 patient [4.2%]. Physical examination showed increased uterine size in 83.3% of cases associated with a latero-uterine mass in 25%. The diagnosis was supported by an ultrasound examination combined with measurement of plasma beta HCG. Histological confirmation was made in all cases and treatment was endo-uterine aspiration. Neoplastic drift was observed in 1 case [4.2%] which went into remission with chemotherapy

[Specific dermatoses of pregnancy]

Pregnancy is a period of endocrinologic, immunological, metabolic and vascular changes during which various cutaneous alterations can be observed. If the physiological modifications are easy to recognize, the diagnosis of pregnancy specific dermatosis are more difficult. Through a correct classification that rests on the exam of elementary lesion, the diagnosis is possible. In case of pruriginous dermatoses, a hepatic check-up including liver enzymes and serum biliary acids must be systematic. The cutaneous biopsy with direct immunofluorescence exam will be done if pemphigoid gestationis is suspected. The treatment remains symptomatic and rests on antipruriginous drugs, dermatotropic corticoids and sometimes cures of corticoids per os. The maternal prognosis is often good. The fetal prognosis is bad in case of high biliary acids level as well as in papulous dermatosis

[Cervical cancer and pregnancy-report of 3 cases and review of the literature]

Cervical carcinoma associated pregnancy is rare relating to only 3 to 17 pregnancies out of 10000 The two principal prognostic factors of cervical cancer which are the stage of disease and the lymphatic spread are associated to other factors concerning the pregnancy which are the term of pregnancy and the mode of delivery The triplet smear-colposcopy-biopsy poses the exact diagnosis in 99,5% of cases, and the colposcopy is indicated each time the smear is suspect or positive, or if a biopsy is necessary in front of a suspect clinical examination This association raises the delicate question of the attitude to adopt with respect to the foetus as well as obstetrical therapeutic We recorded 3 cases in Maternity LALLA MERIEM of the C H U Ibn Rochd of CASABLANCA between 1998 and 2001 as well as a review of the literature in order to elucidate the principal points of the therapeutic