Metronidazole for bacterial vaginosis - a comparison between vaginal gel and oral therapy

To compare the efficacy of 0.75% metronidazole vaginal gel with oral metronidazole for the treatment of bacterial vaginosis. Comparative study, conducted in the Department of Obstetrics and Gynaecology at Ghurki Trust Teaching Hospital attached with Lahore Medical and Dental College, Lahore. The total number of patients included were 290. They were divided into two groups, by random selection. Group A [150 patients] and Group B [140 patients]. 150 patients received metronidazole vaginal gel for 5 days. 98 [85%] patients were free of signs of infection. 11 [9.5%] patients showed partial response and the dose was repeated, while 6 [5.2%] patients showed no response to treatment. 140 patients received metronidazole 400 mg x BD orally for 5 days. In which 80 [77%] patients were free of discharge while 14 [13%] patients and 10 [9.6%] patients showed partial or no response respectively and it was mainly because of gastro-intestinal complaints. Vaginal metronidazole is effective for the treatment of bacterial vaginosis and is associated with better compliance and less side effects as compared to oral metronidazole

Efficacy of fine needle aspiration [FNA] cytology in differentiating malignant and benign ovarian cysts

This study was carried out to determine the diagnostic efficacy of fine needle aspiration cytology between neoplastic and non neoplastic ovarian cysts and to verify the cytological diagnosis of aspirated fluid with histology of excised cyst. This was carried out at the Department of Obstetrics and Gynaecology, Ghurki Trust Teaching Hospital, Lahore from February 2003 to February 2005. It was an analytic study. A total number of 55 patients were included in the study. They were selected on the basis of ultrasonographic examination and having unilocular and non septate ovarian cysts. Ultrasound guided aspiration of cysts was done followed by excision. The cytology of fluid was correlated with histology of excised cyst. Follicular cysts were seen in the highest percentage followed by haemorrhagic luteal cysts, serous cyst adenomas and serous cyst adenocarcinomas. Ultrasound guided fine needle aspiration of ovarian cysts is a feasible alternative to surgery for benign cysts of the ovary

Vulval mass

Miss T, daughter of G. N., 25 years of age presented with history of swelling of the right side of the vulva for last 3 years. On examination a large growth arising from the labia majora and hanging down to just below the knee was seen. Excision of the vulval growth was done. Histopathology revealed fibroepithelial polyp

Frequency of hepatitis C in admitted patients of department of obstetrics and gynaecology, ghurki trust teaching hospital, Lahore

To assess the frequency of hepatitis C in admitted patients of department of obstetrics and gynaecology Ghurki trust teaching hospital, Lahore. Descriptive study this study was conducted on patients admitted in obstetrics and gynaecology ward Ghurki trust teaching hospital, Lahore from 1st January 2005 to 31st December 2005. A total of 1569 patients of age between 20 to 70 years were admitted in obstetrics and gynaecology ward Ghurki trust teaching hospital, Lahore and were screened for anti-HCV antibodies by 3rd generation ELISA. All positive patients were asked about previous history of jaundice, surgery, blood transfusion, multiple injections and dental procedures. Out of 1569 patients 107 were found to be anti-HCV positive. Mean age of patients was 34.5 years. Frequency of anti-HCV was maximum [38.3%] in 31-40 years age group and in gynaecology patients [12.5%]. Previous history of multiple injections and dai handling were the most commonly associated factors. Co-existent hepatitis B and C was found in only 2 [1.8%] patients. Hepatitis C is becoming an alarmingly common problem in the area of Ghurki Trust Teaching Hospital, Lahore. Its modes of transmission need to be properly evaluated for its control and prevention

Vesico vaginal fistula after interval debulking in epithelial ovarian cancer

Mrs. S.E, 45 years of age was diagnosed as a case of ovarian carcinoma and had interval debulking, following which she developed vesico-vaginal fistula. Continuous bladder drainage was done for 6 weeks and she was given post operative chemotherapy with cisplatin and gemcitabine. On her 6 weeks postoperative examination, the fistula had healed completely. She is receiving her chemotherapy cycles and is in satisfactory condition

Comparison between single dose versus seven days metronidazole therapy in treatment of trichomonas vaginalis vaginitis

Comparison between single dose use of metronidazole versus seven days therapy in the treatment of trichomonas vaginalis infection. Design and Setting: A one year study from September 2002 to August 2003 conducted at Ghurki Trust Teaching Hospital attached with Lahore Medical and Dental College, Lahore. The total number of patients included are 109. Main Outcome Measure: Comparative treatment results of single dose versus 7 days therapy of metronidazole in treatment of trichomonas vaginalis. 54 patients received metronidazole for 7 days. 51[94.44%] were free of infection. 3 did not respond to treatment and were retreated in the same way. 55 patients received 3 gm single dose treatment. 53% [96.36%] were free of infection while 3 patients required repeat treatment. Conclusions: Single dose treatment is an acceptable option with few side effects and better compliance