RESUMEN
To determine the histopathological patterns of glomerulonephritis according to the clinical presentation. This is a retrospective analysis of light microscopy results of native kidney biopsies done during the period of January 1[st], 2005 until December 31[st], 2008. There were 273 native kidney biopsies performed during this period. Data were collected from the computer data base of Princess Iman Research and Laboratory Center, King Hussein Medical Center, Amman, Jordan. All biopsies were examined by our renal histopathologist. The most common indication was nephrotic syndrome and the most common cause of nephrotic syndrome in our patients was membranous glomerulonephritis. The main cause of subnephrotic proteinuria was minimal change disease and focal and segmental glomerulosclerosis. Membranoproliferative glomerulonephritis was the most frequent finding in patients presenting with microscopic hematuria. In acute nephritis the most common lesions were crescentic, diffuse proliferative and necrotizing glomerulonephritis. Acute tubular necrosis was the most common cause of acute kidney injury. Changes of end stage kidney disease were the most frequent findings in patient with chronic kidney disease. In patients with systemic lupus erythematosus with renal involvement, the most common lesion was class IV lupus nephritis. Kidney biopsy is an extremely helpful investigation and it should be performed once indicated. There is a need for a national registry of kidney biopsies. The histopathological findings are similar to other studies done in Jordan and in the neighboring countries
Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Glomerulonefritis/diagnóstico , Estudios Retrospectivos , Biopsia , Glomerulonefritis Membranosa/epidemiología , Glomerulonefritis Membranoproliferativa , Nefritis Lúpica/epidemiología , Hematuria/etiología , Proteinuria/etiologíaRESUMEN
To identify the prevalence and adequacy of blood pressure control in patients on regular hemodialysis. Seventy-nine patients with end-stage renal disease on regular hemodialysis were studied. The average of 12 blood pressure recordings taken pre- and postdialysis for 12 consecutive dialysis sessions in one month was taken. Patients were classified as hypertensive if their pre- or post-dialysis systolic pressure was above 140 mmHg and diastolic pressure was above 90mmHg. Patients were classified as having controlled blood pressure if systolic blood pressure was = 140mmHg and diastolic blood pressure was = 90mm Hg pre-and post-dialysis with or without antihypertensive drugs. Sixty-one patients [77.2%] were hypertensive. Among the hypertensive patients 41 [67.2%] of them had uncontrolled blood pressure. Twenty-nine patients [70.7%] withheld their antihypertensive drugs predialysis. Time on dialysis, gender, age, bodyweight, hematocrit, and erythropoietin use did not appear to have significant relation to blood pressure control. Interdialytic weight gain was significantly higher in patients with uncontrolled blood pressure. The group with uncontrolled blood pressure had more patients with diabetes mellitus as a cause of their end-stage renal disease. This study showed that hypertension is common and poorly controlled in most patients undergoing chronic hemodialysis. Volume overload is perhaps the major factor in the development of hypertension in this group of patients
Asunto(s)
Humanos , Masculino , Femenino , Prevalencia , Hipertensión/prevención & control , Fallo Renal Crónico/complicaciones , Estudios de Seguimiento , Hipertensión/epidemiología , Presión SanguíneaRESUMEN
To determine the prevalence of hepatitis C antibodies among chronic renal failure patients attending the hemodialysis unit at King Hussein Medical Center, Amman-Jordan. All patients currently attending King Hussein Medical Center for hemodialysis were screened for hepatitis C antibodies using second generation ELISA. The number of patients was 209[130 males [62.2%], 79 females [37.8%]], mean age was 50 years [range 20-75years] One hundred and four tested patients, [57 males [43.8%] and 47 females [59.5%] revealed positive results [p<0.005], giving a total prevalence of 49.8%. The prevalence of HCV antibodies among hemodialysis patients at King Hussein Medical Center was 49.8%. This percentage is higher than Western countries but comparable to some neighboring Arab countries