Aeromonas hydrophila septicaemia and meningitis in a neonate

A 13-day-old boy developed septicaemia and meningitis caused by Aeromonas hydrophila. Treatment with aminoglycosides and cephalosporins was not effective, although, in vitro the organism was susceptible to both antibiotics. The patient improved after combination therapy with co-trimoxazole and piperacillin. The illness was complicated by hydrocephalus. No obvious source of infection was found