Effects of garlic [allium sativum] administration on: 1-serum lipids, lipoproteins and some physiological parameters in healthy male subjects

Garlic has been claimed to be effective against many diseases, a daily ingestion of 4-5 fresh garlic cloves were given to 14 healthy male volunteers along 30 days. Eight healthy male volunteers were served as control, their ages ranged [35-50 years], to evaluate the effects of garlic use on serum total lipids, lipoprotein cholesterol fractions and ratios, cortisol, glucose and liver transaminase enzymes. Garlic consumption produced significant reduction in total lipids, total cholesterol and T-ch/HDL-C ratio, significant increase in HDL-C. No differences in serum triglycrides, LDL-C, HDL C/LDL-C, cortisol, glucose and SOOT, SGPT liver enzymes were observed in comparison to control or before garlic ingestion. The results suggest that garlic may be of some use as lipid lowering agent, hypocholeslerolaemic action and anti-atherosclerosis-related effects

Effects of garlic [allium sativum] administration on: 2- some blood and hemostatic parameters in healthy male subjects

Garlic is a potent spice and medicine with broad therapeutic properties ranging from antibacterial to anticancer. Twenty two healthy male volunteers aged [35-50 years] comprising garlic administered group consumed 4-5 garlic cloves daily for 30 days [N = 14] and control group [N -8] participated in the study, to evaluate the effects of garlic administration on certain blood and hemostatic factors. Garlic ingestion resulted in significant reduction in platelets count, plasma fihrinogen level and longer prothrombin time. No changes in total and ionized calcium, hematocrit value, red blood cells count, serum total protein, albumin andferritin levels were noticed as effect of garlic ingestion. The findings suggest that garlic consumption may be benificial in diseases associated with platelets function, plasma fibrinoly tic activity and thrombosis