RESUMEN
Objective: the study was designed to investigate the effect of aloe vera leaf gel extract on lipid profile parameters like total cholesterol, triglycerides and low density lipoproteins in alloxan induced diabetic rabbits
Material and Methods: the rabbits were made diabetic by injecting alloxan monohydrate and divided in two groups of eight each. Group A was treated with distilled water and Group B was treated with ethanolic extract of aloe vera leaf gel for 28 days. The pre-treatment and posttreatment level of lipid profile parameters were recorded and compared. Statistical analysis was done with help of independent t-test. The effects in two experimental groups were analyzed with help of paired t-test
Results: after 28 days of treatment the mean cholesterol level reduced to 80.9 from 97.1, the mean triglycerides reduced to 149.9 from182.6 and mean LDL reduced to 30.8 from 35.6 mg/dl in the aloe vera group. The mean HDL levels increased to 28.2 from 24.5 mg/dl
Conclusion: there was significant lowering of lipid profile parameters with aloe vera leaf gel extract in alloxan induced diabetic rabbits